Primary Cortisol Deficiency and Growth Hormone Deficiency in a Neonate With Hypoglycemia: Coincidence or Consequence?
Gujral J, Yau M, Yang AC, Kastury R, Romero CJ, Wallach E, Wilkes M, Costin G, Rapaport R. Primary Cortisol Deficiency and Growth Hormone Deficiency in a Neonate With Hypoglycemia: Coincidence or Consequence? Journal Of The Endocrine Society 2019, 3: 838-846. PMID: 30963141, PMCID: PMC6447946, DOI: 10.1210/js.2018-00386.Peer-Reviewed Original ResearchGrowth hormone deficiencyGH deficiencyGH secretionGH levelsSerum cortisolHormone deficiencyIGF-1Receptor defectElevated transaminase levelsRandom GH levelsTransient GH deficiencyEpisodes of hypoglycemiaMelanocortin 2 receptor geneHours of lifeFull-term boyUndetectable serum cortisolPg/mLMolecular genetic testingGlucocorticoid replacementHydrocortisone replacementTransaminase levelsCortisol deficiencyGH therapyNeonatal hypoglycemiaACTH levels