2010
The Human Immune Response to Streptococcal Extracellular Antigens: Clinical, Diagnostic, and Potential Pathogenetic Implications
Johnson DR, Kurlan R, Leckman J, Kaplan EL. The Human Immune Response to Streptococcal Extracellular Antigens: Clinical, Diagnostic, and Potential Pathogenetic Implications. Clinical Infectious Diseases 2010, 50: 481-490. PMID: 20067422, DOI: 10.1086/650167.Peer-Reviewed Original ResearchConceptsAntibody titersImmune responseSingle antibody titerStreptococcal extracellular antigensB antibody titersHuman antibody responseHuman immune responsePaediatric study participantsSymptoms of infectionPotential pathogenetic implicationsThroat culturesGAS infectionAntibody responseSubsequent sequelaePathogenetic mechanismsImmunologic confirmationBlood samplesEpidemiological studiesPathogenetic implicationsStreptococcus antigensCulture resultsStudy participantsImportant human pathogenInfectionExtracellular antigens
2002
Tourette's syndrome
Leckman JF. Tourette's syndrome. The Lancet 2002, 360: 1577-1586. PMID: 12443611, DOI: 10.1016/s0140-6736(02)11526-1.Peer-Reviewed Original Research
1994
"Just right" perceptions associated with compulsive behavior in Tourette's syndrome
Leckman JF, Walker DE, Goodman WK, Pauls DL, Cohen DJ. "Just right" perceptions associated with compulsive behavior in Tourette's syndrome. American Journal Of Psychiatry 1994, 151: 675-680. PMID: 8166308, DOI: 10.1176/ajp.151.5.675.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge of OnsetAgedAwarenessBasal GangliaChildComorbidityCompulsive BehaviorCross-Sectional StudiesFemaleHumansMaleMiddle AgedObsessive BehaviorObsessive-Compulsive DisorderPerceptionPersonality InventoryPsychiatric Status Rating ScalesSensationSeverity of Illness IndexTourette SyndromeConceptsTic disordersObsessive-compulsive disorderTourette syndromeObsessive-compulsive symptomsCompulsive behaviorsCross-sectional studyYale-Brown Obsessive Compulsive ScaleObsessive Compulsive ScaleTic symptomsChronic disordersPhonic ticsChildhood onsetEpidemiological studiesSyndromeAdult subjectsBrain regionsSymptomsCompulsive ScaleDisordersSensorimotor informationSubjectsThree-quartersCompulsive actsPathobiologySeverity
1993
Premonitory urges in Tourette's syndrome
Leckman JF, Walker DE, Cohen DJ. Premonitory urges in Tourette's syndrome. American Journal Of Psychiatry 1993, 150: 98-102. PMID: 8417589, DOI: 10.1176/ajp.150.1.98.Peer-Reviewed Original ResearchConceptsTic disordersPremonitory urgesTourette syndromeYale Global Tic Severity ScaleHyperkinetic movement disordersCross-sectional studyTic Severity ScaleVoluntary responseMidline abdomenTic symptomsPhonic ticsMovement disordersEpidemiological studiesSeverity ScaleCase findingTic severityPrevalence dataAdult subjectsBrain regionsSyndromeTic behaviorsInvoluntary motorFeeling of reliefDisordersAnatomical regions