2018
Adaptive treatment strategies for children and adolescents with Obsessive-Compulsive Disorder: A sequential multiple assignment randomized trial
Fatori D, de Bragança Pereira CA, Asbahr FR, Requena G, Alvarenga PG, de Mathis MA, Rohde LA, Leckman JF, March JS, Polanczyk GV, Miguel EC, Shavitt RG. Adaptive treatment strategies for children and adolescents with Obsessive-Compulsive Disorder: A sequential multiple assignment randomized trial. Journal Of Anxiety Disorders 2018, 58: 42-50. PMID: 30025255, DOI: 10.1016/j.janxdis.2018.07.002.Peer-Reviewed Original ResearchConceptsGroup cognitive behavioral therapySequential multiple assignmentTreatment failureInitial treatmentBaseline Yale-Brown ObsessiveChildhood OCDEffective initial treatmentProvision of treatmentCompulsive Scale scoresCognitive behavioral therapyAdaptive treatment strategiesYale-Brown ObsessiveSame regimenObsessive-compulsive disorderTreatment strategiesSymptom reductionPrimary analysisScale scoreFluoxetineTime pointsWeeksTreatmentChildrenEffect sizeTrials
2007
Obsessive-Compulsive Disorder: An Open-Label Pilot Trial of Escitalopram
Galvão-de Almeida A, Quarantini LC, Góis CR, Santos-Jesus R, Miranda-Scippa AM, de Oliveira IR, da Silva Prado H, Leckman JF, Rosário MC. Obsessive-Compulsive Disorder: An Open-Label Pilot Trial of Escitalopram. CNS Spectrums 2007, 12: 519-524. PMID: 17603402, DOI: 10.1017/s1092852900021258.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderYale-Brown ObsessiveTreatment responseOpen-label pilot trialSelective serotonin reuptake inhibitorsFourth Edition Axis IOpen-label studySerotonin reuptake inhibitorsOpen-label natureEdition Axis IStructured Clinical InterviewTotal Yale-Brown ObsessiveCompulsive Scale scoresReuptake inhibitorsDosage adjustmentNew medicationsPilot trialAxis IClinical InterviewPatientsScale scoreEscitalopramExperienced psychiatristsMental disordersUseful option