2016
Effective Translation of an Intensive Lifestyle Intervention for Hispanic Women With Prediabetes in a Community Health Center Setting
Van Name MA, Camp AW, Magenheimer EA, Li F, Dziura JD, Montosa A, Patel A, Tamborlane WV. Effective Translation of an Intensive Lifestyle Intervention for Hispanic Women With Prediabetes in a Community Health Center Setting. Diabetes Care 2016, 39: 525-531. PMID: 26908915, PMCID: PMC4806769, DOI: 10.2337/dc15-1899.Peer-Reviewed Original ResearchMeSH KeywordsAdiposityAdolescentAdultAgedBody Mass IndexChoice BehaviorCommunity Health CentersDiabetes Mellitus, Type 2ExerciseFeasibility StudiesFemaleFood PreferencesHispanic or LatinoHumansInsulinLife StyleMiddle AgedPilot ProjectsPrediabetic StateRisk FactorsSocioeconomic FactorsWaist CircumferenceWeight LossYoung AdultConceptsIntensive lifestyle interventionDiabetes Prevention ProgramCommunity health center settingUsual care groupType 2 diabetesHealth center settingHispanic womenILI groupLifestyle interventionCare groupOral glucose tolerance testCenter settingLow-income Hispanic womenWeight lossSimilar baseline weightGlucose tolerance testPercent body fatType of interventionCHC settingsDPP interventionsUsual careBaseline weightWaist circumferenceGlucose excursionsTolerance test
2011
Long-term Results of an Obesity Program in an Ethnically Diverse Pediatric Population
Savoye M, Nowicka P, Shaw M, Yu S, Dziura J, Chavent G, O'Malley G, Serrecchia JB, Tamborlane WV, Caprio S. Long-term Results of an Obesity Program in an Ethnically Diverse Pediatric Population. Pediatrics 2011, 127: 402-410. PMID: 21300674, PMCID: PMC3065145, DOI: 10.1542/peds.2010-0697.Peer-Reviewed Original ResearchConceptsControl groupLow-density lipoprotein cholesterolTotal body fat massIntensive lifestyle programIntensive lifestyle interventionHomeostasis model assessmentActive intervention phaseWeight management programBody fat massLong-term resultsBMI z-scorePercent body fatDiverse pediatric populationFamily-based programsLifestyle interventionLipoprotein cholesterolTotal cholesterolObese childrenObese populationPediatric populationInsulin resistanceObesity programLifestyle programFat massIntervention group
2010
Apolipoprotein C3 Gene Variants in Nonalcoholic Fatty Liver Disease
Petersen KF, Dufour S, Hariri A, Nelson-Williams C, Foo JN, Zhang XM, Dziura J, Lifton RP, Shulman GI. Apolipoprotein C3 Gene Variants in Nonalcoholic Fatty Liver Disease. New England Journal Of Medicine 2010, 362: 1082-1089. PMID: 20335584, PMCID: PMC2976042, DOI: 10.1056/nejmoa0907295.Peer-Reviewed Original ResearchConceptsNonalcoholic fatty liver diseaseFatty liver diseasePlasma triglyceride clearanceLiver diseaseFat tolerance testPlasma triglyceride concentrationsInsulin resistanceApolipoprotein C3Wild-type homozygotesIndian menTriglyceride clearanceTriglyceride concentrationsC3 concentrationsTriglyceride contentApolipoprotein C3 gene variantsHealthy Asian Indian menOral fat tolerance testType 2 diabetes mellitusVariant allelesIntravenous fat tolerance testLiver triglyceride contentHepatic triglyceride contentSingle nucleotide polymorphismsVariant allele carriersHepatic insulin resistance
2008
Effect of a Successful Intensive Lifestyle Program on Insulin Sensitivity and Glucose Tolerance in Obese Youth
Shaw M, Savoye M, Cali A, Dziura J, Tamborlane WV, Caprio S. Effect of a Successful Intensive Lifestyle Program on Insulin Sensitivity and Glucose Tolerance in Obese Youth. Diabetes Care 2008, 32: 45-47. PMID: 18840769, PMCID: PMC2606827, DOI: 10.2337/dc08-0808.Peer-Reviewed Original ResearchConceptsIntensive lifestyle programLifestyle programInsulin sensitivityObese youthBody fatGlucose metabolismLarge randomized clinical trialsOral glucose tolerance testGlucose tolerance testRandomized clinical trialsGlucose toleranceObese childrenControl subjectsTolerance testClinical trialsBody compositionBody weightSubject changesGreater decreaseSubjectsFatMetabolismBMIResearch designBright bodiesSocioeconomic predictors of weight loss after laparoscopic Roux-Y gastric bypass
Akkary E, Nerlinger A, Yu S, Dziura J, Duffy AJ, Bell RL. Socioeconomic predictors of weight loss after laparoscopic Roux-Y gastric bypass. Surgical Endoscopy 2008, 23: 1246-1251. PMID: 18813989, DOI: 10.1007/s00464-008-0138-z.Peer-Reviewed Original ResearchConceptsBody mass indexInitial body mass indexPostoperative weight lossWeight lossLaparoscopic RouxBMI decreaseSocioeconomic statusInitial mean body mass indexMedian household incomeMean body mass indexPrivate insuranceAppropriate patient selectionPrivate insurance groupPostoperative behavioral changesInsurance carriersProspective databaseGastric bypassPatient demographicsSingle surgeonMass indexPatient selectionGroup APatientsLRYGBHousehold incomeThe paradox of the pouch: prompt emptying predicts improved weight loss after laparoscopic Roux-Y gastric bypass
Akkary E, Sidani S, Boonsiri J, Yu S, Dziura J, Duffy AJ, Bell RL. The paradox of the pouch: prompt emptying predicts improved weight loss after laparoscopic Roux-Y gastric bypass. Surgical Endoscopy 2008, 23: 790. PMID: 18806946, DOI: 10.1007/s00464-008-0069-8.Peer-Reviewed Original ResearchConceptsWeight lossGastric bypassLaparoscopic RouxOperative timeGastric pouchSlow emptyingAnalysis of covarianceBody mass index lossLinear stapler techniqueUpper gastrointestinal evaluationGroup B patientsPostoperative day 1Postoperative weight lossInfluences weight lossLength of stayMore weight lossAnastomotic edemaUGI studiesProspective databaseRate of contrastB patientsGastrointestinal evaluationPatient demographicsSingle surgeonNormal gastric
2007
Effects of a Weight Management Program on Body Composition and Metabolic Parameters in Overweight Children: A Randomized Controlled Trial
Savoye M, Shaw M, Dziura J, Tamborlane WV, Rose P, Guandalini C, Goldberg-Gell R, Burgert TS, Cali AM, Weiss R, Caprio S. Effects of a Weight Management Program on Body Composition and Metabolic Parameters in Overweight Children: A Randomized Controlled Trial. JAMA 2007, 297: 2697-2704. PMID: 17595270, DOI: 10.1001/jama.297.24.2697.Peer-Reviewed Original ResearchConceptsWeight management programWeight management groupOverweight childrenMetabolic complicationsInsulin resistanceBody fatBody compositionControl groupArray of comorbiditiesMost overweight childrenSix-month improvementsHomeostasis model assessmentPediatric obesity clinicSerious metabolic complicationWeight management counselingType 2 diabetesMajor health issueFamily-based programsMixed ethnic groupsMonths of studyHOMA-IRObesity clinicOverweight adultsControlled TrialsPediatric obesity
2005
Anthropometric and psychosocial changes in obese adolescents enrolled in a Weight Management Program
Savoye M, Berry D, Dziura J, Shaw M, Serrecchia JB, Barbetta G, Rose P, Lavietes S, Caprio S. Anthropometric and psychosocial changes in obese adolescents enrolled in a Weight Management Program. Journal Of The Academy Of Nutrition And Dietetics 2005, 105: 364-370. PMID: 15746823, DOI: 10.1016/j.jada.2004.12.009.Peer-Reviewed Original ResearchConceptsBMI z-scoreWeight management programBody fat percentNondiet approachObese adolescentsZ-scoreComprehensive weight management programSuperior short-term resultsBody mass index z-scoreEntire groupFat percentStructured meal planImproved long-term resultsLong-term resultsIndex z-scoreShort-term resultsBetter food choicesDietary ApproachesLong-term effectsCovariance pattern modelMeal planPsychosocial changesOutcome variablesManagement programScores
2004
Can Physical Activity Attenuate Aging-related Weight Loss in Older People?
Dziura J, Mendes de Leon C, Kasl S, DiPietro L. Can Physical Activity Attenuate Aging-related Weight Loss in Older People? American Journal Of Epidemiology 2004, 159: 759-767. PMID: 15051585, DOI: 10.1093/aje/kwh105.Peer-Reviewed Original ResearchMeSH KeywordsAgedAgingBody WeightConnecticutExerciseFemaleHumansLongitudinal StudiesMaleRegression AnalysisWeight LossConceptsPhysical activityBody weightWeight lossAge-related weight lossDisease-related weight lossOlder peopleBaseline body weightTotal activity scoreFrail older peopleEntire followActivity scoreChronic diseasesEpidemiologic studiesOlder ageWeight changeEstablished PopulationsOlder cohortRandom effects regressionNew HavenRate of agingCohortFollowYearsActivityDisease