2016
Weight Gain and Metabolic Consequences of Risperidone in Young Children With Autism Spectrum Disorder
Scahill L, Jeon S, Boorin SJ, McDougle CJ, Aman MG, Dziura J, McCracken JT, Caprio S, Arnold LE, Nicol G, Deng Y, Challa SA, Vitiello B. Weight Gain and Metabolic Consequences of Risperidone in Young Children With Autism Spectrum Disorder. Journal Of The American Academy Of Child & Adolescent Psychiatry 2016, 55: 415-423. PMID: 27126856, PMCID: PMC4851735, DOI: 10.1016/j.jaac.2016.02.016.Peer-Reviewed Original ResearchConceptsWaist circumferenceWeight gainWeek 24Metabolic syndromeWeek 16Homeostatic model assessment-insulin resistanceMetabolic consequencesModel assessment-insulin resistanceBody mass index z-scoreAssessment-insulin resistanceLiver function testsTrial of risperidoneIndex z-scoreAutism spectrum disorderRapid weight gainRisperidone exposureBlood lipidsRisperidone monotherapyRisperidone treatmentFunction testsNormal weightInsulin resistanceAlanine aminotransferaseSpectrum disorderBlood samples
2012
Use of a Direct Observational Measure in a Trial of Risperidone and Parent Training in Children with Pervasive Developmental Disorders
Handen BL, Johnson CR, Butter EM, Lecavalier L, Scahill L, Aman MG, McDougle CJ, Arnold LE, Swiezy NB, Sukhodolsky DG, Mulick JA, White SW, Bearss K, Hollway JA, Stigler KA, Dziura J, Yu S, Sacco K, Vitiello B. Use of a Direct Observational Measure in a Trial of Risperidone and Parent Training in Children with Pervasive Developmental Disorders. Journal Of Developmental And Physical Disabilities 2012, 25: 355-371. PMID: 23730123, PMCID: PMC3665525, DOI: 10.1007/s10882-012-9316-y.Peer-Reviewed Original ResearchParent trainingPositive reinforcementChild's inappropriate behaviorParent-child interactionsAutism spectrum disorderDirect observational measuresTrial of risperidoneSerious behavior problemsPervasive developmental disorderAnalysis of covarianceClinician-based measuresParent behaviorSpectrum disorderObservational measuresAnalogue measuresBehavior problemsInappropriate behaviorDevelopmental disordersAnalog procedureParentsParental requestChildrenTreatment conditionsGreater useMeasures