2020
Effects of Accounting for Interval-Censored Antibody Titer Decay on Seroincidence in a Longitudinal Cohort Study of Leptospirosis
Bonner K, Cruz JS, Sacramento GA, de Oliveira D, Nery N, Carvalho M, Costa F, Childs JE, Ko AI, Diggle PJ. Effects of Accounting for Interval-Censored Antibody Titer Decay on Seroincidence in a Longitudinal Cohort Study of Leptospirosis. American Journal Of Epidemiology 2020, 190: 893-899. PMID: 33274738, PMCID: PMC8096484, DOI: 10.1093/aje/kwaa253.Peer-Reviewed Original ResearchMeSH KeywordsBrazilHumansIncidenceItalyLeptospirosisLongitudinal StudiesRisk FactorsSeroepidemiologic StudiesConceptsLongitudinal cohort studyCohort studyMicroscopic agglutination test titersAgglutination test titersHigh transmission settingsPoint-source exposureSeroincidence ratesEstimates of infectionRisk factorsTest titersReported casesEpidemiologic implicationsInfection rateMean infection rateSerological samplesSerological assaysLeptospirosis casesInfectionArboviral diseasesTiter dilutionsSeroincidenceSource exposureLeptospirosisSample size estimationInterval
2001
Persistent infection in Neotoma fuscipes (Muridae: Sigmodontinae) with Ehrlichia phagocytophila sensu lato.
Castro M, Nicholson W, Kramer V, Childs J. Persistent infection in Neotoma fuscipes (Muridae: Sigmodontinae) with Ehrlichia phagocytophila sensu lato. American Journal Of Tropical Medicine And Hygiene 2001, 65: 261-7. PMID: 11693866, DOI: 10.4269/ajtmh.2001.65.261.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, BacterialArachnid VectorsBase SequenceBorrelia burgdorferiCaliforniaDisease ReservoirsDNA, BacterialEhrlichiaEhrlichiosisFemaleFluorescent Antibody Technique, IndirectHeat-Shock ProteinsHumansIxodesMaleMicePolymerase Chain ReactionRatsRodent DiseasesSeasonsSeroepidemiologic StudiesSigmodontinaeZoonosesConceptsPolymerase chain reaction testingGroESL heat shock operonPersistent infectionReaction testingRatsE. phagocytophilaLyme diseaseBorrelia burgdorferiMiceSeropositive animalsDusky-footed wood ratsPCRWood ratsSeroreversionSensu latoSeroconversionSeropositiveBiopsySerologySeroreactivityInfectionDiseaseBloodAdult Ixodes pacificus CooleySerumSerologic evidence of Rickettsia akari infection among dogs in a metropolitan city.
Comer J, Vargas M, Poshni I, Childs J. Serologic evidence of Rickettsia akari infection among dogs in a metropolitan city. Journal Of The American Veterinary Medical Association 2001, 218: 1780-2. PMID: 11394829, DOI: 10.2460/javma.2001.218.1780.Peer-Reviewed Original ResearchConceptsIndirect immunofluorescence antibodyEnzyme immunoassaySerum samplesPossible risk factorsFever group rickettsiaeClinical illnessRoutine careSerologic evidenceSeropositive dogsRisk factorsTime serum samplesIFA testingClinical relevanceImmunofluorescence antibodySerologic surveyRickettsia akariInfectionGroup rickettsiaeDogsTitersCausative agentVeterinary clinicsFurther studiesDog ownersTick infestation
2000
DETECTION OF ANTIBODIES REACTIVE WITH EHRLICHIA CHAFFEENSIS IN THE RACCOON
Comer J, Nicholson W, Paddock C, Sumner J, Childs J. DETECTION OF ANTIBODIES REACTIVE WITH EHRLICHIA CHAFFEENSIS IN THE RACCOON. Journal Of Wildlife Diseases 2000, 36: 705-712. PMID: 11085432, DOI: 10.7589/0090-3558-36.4.705.Peer-Reviewed Original Research
1999
Serologic evidence of rickettsialpox (Rickettsia akari) infection among intravenous drug users in inner-city Baltimore, Maryland.
Comer J, Tzianabos T, Flynn C, Vlahov D, Childs J. Serologic evidence of rickettsialpox (Rickettsia akari) infection among intravenous drug users in inner-city Baltimore, Maryland. American Journal Of Tropical Medicine And Hygiene 1999, 60: 894-8. PMID: 10403316, DOI: 10.4269/ajtmh.1999.60.894.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, BacterialBaltimoreCohort StudiesCross ReactionsDrinkingFemaleFluorescent Antibody Technique, IndirectHIV SeropositivityHumansIll-Housed PersonsMaleRickettsiaRickettsia InfectionsRickettsia rickettsiiRisk FactorsSeroepidemiologic StudiesSubstance Abuse, IntravenousUrban PopulationConceptsIntravenous drug usersInner-city BaltimoreDrug usersSerologic evidenceSerum samplesAcute febrile illnessR. rickettsiiR. akariHuman immunodeficiency virusSignificant risk factorsSignificant inverse associationCross-adsorption studiesPresence of antibodiesSingle serum sampleR. akari infectionFrequency of injectionsFever group rickettsiaeFebrile illnessUndetermined etiologyImmunodeficiency virusInverse associationRisk factorsGroup-specific antibodiesDrug useHigh titersHantavirus (Bunyaviridae) infections in rodents from Orange and San Diego counties, California.
Bennett S, Webb J, Madon M, Childs J, Ksiazek T, Torrez-Martinez N, Hjelle B. Hantavirus (Bunyaviridae) infections in rodents from Orange and San Diego counties, California. American Journal Of Tropical Medicine And Hygiene 1999, 60: 75-84. PMID: 9988327, DOI: 10.4269/ajtmh.1999.60.75.Peer-Reviewed Original ResearchConceptsHantavirus antibodiesHarvest miceReverse transcription-polymerase chain reactionTranscription-polymerase chain reactionDeer miceEl Moro Canyon virusBroad geographic rangeMale deer miceMajority of rodentsSNV antibodyAntibody-positive rodentsSan Diego CountyVirus antibodiesAntibody prevalenceHantavirus infectionSeropositive rodentsMicrohabitat selectionCactus mouseGeographic rangeFood plantsWestern blotHost distributionMiceCalifornia volesP. maniculatus
1997
Patterns of association with host and habitat: antibody reactive with Sin Nombre virus in small mammals in the major biotic communities of the southwestern United States.
Mills J, Ksiazek T, Ellis B, Rollin P, Nichol S, Yates T, Gannon W, Levy C, Engelthaler D, Davis T, Tanda D, Frampton J, Nichols C, Peters C, Childs J. Patterns of association with host and habitat: antibody reactive with Sin Nombre virus in small mammals in the major biotic communities of the southwestern United States. American Journal Of Tropical Medicine And Hygiene 1997, 56: 273-84. PMID: 9129529, DOI: 10.4269/ajtmh.1997.56.273.Peer-Reviewed Original ResearchConceptsBiotic communitiesDeer miceSmall mammalsBrush miceWestern harvest miceLower Sonoran DesertMajor biotic communitiesSouthwestern United StatesDesert habitatsMontane forestsHarvest miceSonoran DesertMammalsHabitatsSin Nombre virusHorizontal transmissionClimatic extremesNombre virusInfected deer mice
1995
Ehrlichiosis in a Golf-Oriented Retirement Community
Standaert S, Dawson J, Schaffner W, Childs J, Biggie K, Singleton J, Gerhardt R, Knight M, Hutcheson R. Ehrlichiosis in a Golf-Oriented Retirement Community. New England Journal Of Medicine 1995, 333: 420-425. PMID: 7616991, DOI: 10.1056/nejm199508173330704.Peer-Reviewed Original ResearchConceptsE. chaffeensis infectionCase-control studySerologic testingCommunity AMedical history reviewLone star tickRisk of infectionCommunity BAnnual incidenceSerologic evidencePolymerase chain reactionTick biteRetirement communityInfectionEhrlichiosisEndemic diseaseChain reactionEhrlichia chaffeensisHigh rateSurvey participantsPercentTicksInsect repellentOutbreakRecreational activities
1994
Prevalence of infection with Junin virus in rodent populations in the epidemic area of Argentine hemorrhagic fever.
Mills J, Ellis B, Childs J, McKee K, Maiztegui J, Peters C, Ksiazek T, Jahrling P. Prevalence of infection with Junin virus in rodent populations in the epidemic area of Argentine hemorrhagic fever. American Journal Of Tropical Medicine And Hygiene 1994, 51: 554-62. PMID: 7985747, DOI: 10.4269/ajtmh.1994.51.554.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAnimalsAntibodies, ViralAntigens, ViralArgentinaArvicolinaeCarnivoraDisease ReservoirsEnzyme-Linked Immunosorbent AssayFemaleFluorescent Antibody TechniqueHemorrhagic Fever, AmericanJunin virusMaleMuridaePopulation DynamicsPrevalenceRodent DiseasesRodentiaSalivaSeroepidemiologic StudiesSex FactorsConceptsC. musculinusC. lauchaArgentine hemorrhagic feverCrop habitatsJunin virusBody mass classesGalictis cujaPredatory carnivoresHemorrhagic feverInfected speciesSmall mammalsMark-recapture gridsEpidemic areasPrincipal reservoir speciesBolomys obscurusHabitatsReservoir populationsRodent populationsCalomys musculinusSeropositive animalsIndirect fluorescent antibodySpeciesReservoir speciesPrevalence of infectionHorizontal transmissionLongitudinal Study of Borrelia burgdorferi Infection in New Jersey Outdoor Workers, 1988–1991
Schwartz B, Goldstein M, Childs J. Longitudinal Study of Borrelia burgdorferi Infection in New Jersey Outdoor Workers, 1988–1991. American Journal Of Epidemiology 1994, 139: 504-512. PMID: 8154474, DOI: 10.1093/oxfordjournals.aje.a117033.Peer-Reviewed Original ResearchConceptsRisk factorsRural residenceSeroconversion of antibodiesBorrelia burgdorferi infectionLyme disease seroprevalenceAntibody seropositivitySerologic statusOdds ratioBurgdorferi infectionTick exposureSeroconversionElevated riskHigh riskOutdoor workersAnnual questionnairesMedical problemsLyme diseaseDisease seroprevalenceSeroprevalenceBorrelia burgdorferiLongitudinal studySeropositivityPet ownershipRural residentsRiskDomestic Cases of Hemorrhagic Fever with Renal Syndrome in the United States
Glass G, Watson A, LeDuc J, Childs J. Domestic Cases of Hemorrhagic Fever with Renal Syndrome in the United States. Nephron 1994, 68: 48-51. PMID: 7991040, DOI: 10.1159/000188086.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, ViralFemaleHantaan virusHemorrhagic Fever with Renal SyndromeHumansLiverMaleMiddle AgedProteinuriaRetrospective StudiesSeroepidemiologic StudiesUnited StatesConceptsRenal diseaseHantaviral infectionsHemorrhagic feverRenal syndromeHypertensive renal diseasePersistent hypertensionLiver failureMild illnessClinical featuresSerologic studiesAcute diseaseSeoul virusInfectionDiseaseFeverSyndromeUnited StatesVirusFurther evidenceHypertensionNauseaVomitingPatientsIllnessDomestic cases
1993
Antibodies to Borrelia burgdorferi and tick salivary gland proteins in New Jersey outdoor workers.
Schwartz B, Goldstein M, Childs J. Antibodies to Borrelia burgdorferi and tick salivary gland proteins in New Jersey outdoor workers. American Journal Of Public Health 1993, 83: 1746-8. PMID: 8259808, PMCID: PMC1694949, DOI: 10.2105/ajph.83.12.1746.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnimalsAntibodiesAntibodies, BacterialArachnid VectorsBorrelia burgdorferi GroupCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayFemaleFollow-Up StudiesHumansLyme DiseaseMaleNew JerseyOccupational DiseasesPrevalenceRisk FactorsSalivary Proteins and PeptidesSeroepidemiologic StudiesSurveys and QuestionnairesTicksWorkplaceConceptsOutdoor workersBorrelia burgdorferiCross-sectional studyB. burgdorferi infectionSecond cross-sectional studyEnzyme-linked immunosorbentLyme disease seroprevalenceAntibody seropositivitySalivary gland proteinsBurgdorferi infectionTick exposureHigh riskLyme diseaseDisease seroprevalenceAntibodiesBurgdorferiGland proteinsSeropositivitySeroprevalenceInfectionPrevalenceDiseaseImmunosorbentWorkers
1992
Risk factors associated with antibodies to leptospires in inner-city residents of Baltimore: a protective role for cats.
Childs J, Schwartz B, Ksiazek T, Graham R, LeDuc J, Glass G. Risk factors associated with antibodies to leptospires in inner-city residents of Baltimore: a protective role for cats. American Journal Of Public Health 1992, 82: 597-599. PMID: 1546785, PMCID: PMC1694107, DOI: 10.2105/ajph.82.4.597.Peer-Reviewed Original Research