1979
The paracellular pathway and bile formation.
Boyer J, Elias E, Layden T. The paracellular pathway and bile formation. The Yale Journal Of Biology And Medicine 1979, 52: 61-7. PMID: 452623, PMCID: PMC2595701.Peer-Reviewed Original Research
1977
Taurolithocholate-Induced Cholestasis: Taurocholate, but not Dehydrocholate, Reverses Cholestasis and Bile Canalicular Membrane Injury
Layden T, Boyer J. Taurolithocholate-Induced Cholestasis: Taurocholate, but not Dehydrocholate, Reverses Cholestasis and Bile Canalicular Membrane Injury. Gastroenterology 1977, 73: 120-128. PMID: 863183, DOI: 10.1016/s0016-5085(19)32283-8.Peer-Reviewed Original ResearchEffects of chronic choleretic infusions of bile acids on the membrane of the bile canaliculus. A biochemical and morphologic study.
Nemchausky B, Layden T, Boyer J. Effects of chronic choleretic infusions of bile acids on the membrane of the bile canaliculus. A biochemical and morphologic study. Laboratory Investigation 1977, 36: 259-67. PMID: 138767.Peer-Reviewed Original Research
1975
Scanning Electron Microscopy of the Rat Liver Studies of the effect of taurolithocholate and other models of cholestasis
Layden T, Schwarz J, Boyer J. Scanning Electron Microscopy of the Rat Liver Studies of the effect of taurolithocholate and other models of cholestasis. Gastroenterology 1975, 69: 724-738. PMID: 1158090, DOI: 10.1016/s0016-5085(19)32475-8.Peer-Reviewed Original ResearchConceptsModel of cholestasisBile duct ligationEstradiol treatmentDuct ligationEffect of cholestasisEffect of taurolithocholateTLC-induced cholestasisDirect toxic effectBile canaliculiLithocholate sulfateRat liver studiesCanalicular membraneLoss of microvilliNormal findingsFinger fracturesPortal veinDistinctive abnormalitiesSimultaneous infusionCholestasisSodium taurolithocholateSevere abnormalitiesSodium taurocholateInfusionTaurolithocholateLiver studies