1998
Role of glutathione in hepatic bile formation during reperfusion after cold ischemia of the rat liver
Koeppel T, Trauner M, Albert M, Arrese M, Rios-Velez L, Boyer J. Role of glutathione in hepatic bile formation during reperfusion after cold ischemia of the rat liver. Journal Of Hepatology 1998, 28: 812-819. PMID: 9625316, DOI: 10.1016/s0168-8278(98)80231-6.Peer-Reviewed Original ResearchConceptsBiliary glutathione excretionBile duct injuryCold ischemiaBile flowHepatic bile formationDuct injuryLiver transplantationBiliary tractBiliary excretionRat liverGlutathione excretionBasal bile flow ratesBile formationBile acid-independent bile flowOxidative stressLate reperfusion periodBile duct damageBile flow rateOnset of reperfusionIndependent bile flowBile duct morphologyBiliary glutathione concentrationsWistar rat liverLiver reperfusionDuct damage
1988
Biliary catabolism of glutathione and differential reabsorption of its amino acid constituents
Ballatori N, Jacob R, Barrett C, Boyer J. Biliary catabolism of glutathione and differential reabsorption of its amino acid constituents. American Journal Of Physiology 1988, 254: g1-g7. PMID: 2892423, DOI: 10.1152/ajpgi.1988.254.1.g1.Peer-Reviewed Original ResearchConceptsGuinea pigsBile samplesAT-125Biliary glutathione excretionControl bile samplesHepatic gamma-glutamyltransferase activityCatabolism of glutathioneTotal amino acidsGamma-glutamyltransferase activityBiliary treePentobarbital sodiumBiliary excretionHepatic bileAmino acid conjugationGlutathione excretionRetrograde intrabiliary infusionBileConcentration of glutathioneFree amino acidsTotal glutamateConstituent amino acidsMarked increaseUndetectable levelsAcid conjugationDogs