1989
Hepatic immunohistochemical localization of the tight junction protein ZO-1 in rat models of cholestasis.
Anderson J, Glade J, Stevenson B, Boyer J, Mooseker M. Hepatic immunohistochemical localization of the tight junction protein ZO-1 in rat models of cholestasis. American Journal Of Pathology 1989, 134: 1055-62. PMID: 2719075, PMCID: PMC1879891.Peer-Reviewed Original ResearchConceptsZO-1 proteinZO-1Tight junctionsConsecutive daily subcutaneous injectionsFrozen sectionsReflux of bileDaily subcutaneous injectionsBile duct obstructionCommon bile ductMale Sprague-DawleyHepatocyte tight junctionsBile duct ligation resultsTight junction protein ZO-1Cholestatic modelsDuct obstructionBile ductSubcutaneous injectionCholestatic liverRat modelEthinyl estradiolSprague-DawleyProtein ZO-1Immunoperoxidase stainingZO-1 stainingImmunohistochemical localization
1974
Hepatic Injury from Chronic Hypervitaminosis a Resulting in Portal Hypertension and Ascites
Russell R, Boyer J, Bagheri S, Hruban Z. Hepatic Injury from Chronic Hypervitaminosis a Resulting in Portal Hypertension and Ascites. New England Journal Of Medicine 1974, 291: 435-440. PMID: 4843409, DOI: 10.1056/nejm197408292910903.Peer-Reviewed Original ResearchMeSH KeywordsAscitesBasement MembraneBiopsy, NeedleChemical and Drug Induced Liver InjuryCollagenFemaleHepatic VeinsHistocytochemistryHumansHypertension, PortalLipid MetabolismLiverLiver CirculationLiver CirrhosisMaleMicroscopy, ElectronMicroscopy, FluorescenceMiddle AgedSclerosisTime FactorsVitamin AConceptsPortal hypertensionHepatic blood flowChronic hypervitaminosis ALiver biopsy materialLipid storage cellsChronic hypervitaminosisFocal congestionVein sclerosisHepatic injuryPerisinusoidal fibrosisHypervitaminosis AChronic ingestionHepatic functionClinical signsHistologic examinationBlood flowUnusual lesionFrozen sectionsIto cellsPerisinusoidal spaceCirrhosisHypertensionAscitesVitaminLike material