2020
Quantifying treatment selection bias effect on survival in comparative effectiveness research: findings from low-risk prostate cancer patients
Miccio JA, Talcott WJ, Jairam V, Park HS, Yu JB, Leapman MS, Johnson SB, King MT, Nguyen PL, Kann BH. Quantifying treatment selection bias effect on survival in comparative effectiveness research: findings from low-risk prostate cancer patients. Prostate Cancer And Prostatic Diseases 2020, 24: 414-422. PMID: 32989262, DOI: 10.1038/s41391-020-00291-3.Peer-Reviewed Original ResearchConceptsProstate cancer-specific survivalLow-risk prostate cancerExternal beam radiotherapyTreatment selection biasOverall survivalRadical prostatectomyProstate cancerOS differenceLow-risk prostate cancer patientsCancer-specific survivalEnd Results (SEER) databaseProstate cancer patientsClinical trial designEffectiveness researchComparative effectiveness researchPropensity-score matchingMethodsThe SurveillanceTreatment guidelinesResults databaseEntire cohortResultsA totalCancer patientsTreatment modalitiesNational registryPatient managementUltrahypofractionated versus hypofractionated and conventionally fractionated radiation therapy for localized prostate cancer: A systematic review and meta-analysis of phase III randomized trials
Lehrer E, Kishan A, Yu J, Trifiletti D, Showalter T, Ellis R, Zaorsky N. Ultrahypofractionated versus hypofractionated and conventionally fractionated radiation therapy for localized prostate cancer: A systematic review and meta-analysis of phase III randomized trials. Radiotherapy And Oncology 2020, 148: 235-242. PMID: 32505965, DOI: 10.1016/j.radonc.2020.04.037.Peer-Reviewed Original ResearchConceptsConventionally fractionated radiation therapyHypofractionated radiation therapyUltrahypofractionated radiation therapyLate grade 2Radiation therapyGrade 2Weighted random effects meta-analysesSummary effect sizesLocalized prostate cancerCompare treatment modalitiesDerSimonian and Laird methodPhase III protocolsRandom-effects meta-analysesGenitourinary toxicityEffects meta-analysesGastrointestinal toxicityProspective trialsMedian ageProstate cancerTreatment modalitiesComparing patientsIII protocolLaird methodTherapyMeta-analysis
2019
Comparative Effectiveness of SBRT
Aneja S, Kumar R, Yu J. Comparative Effectiveness of SBRT. 2019, 415-424. DOI: 10.1007/978-3-030-16924-4_34.Peer-Reviewed Original ResearchStereotactic body radiation therapyAlternative treatment modalityBody radiation therapyComparative effectiveness studiesCost-effectiveness studiesLarge database analysisRetrospective seriesTreatment modalitiesRadiation therapySBRT treatmentComparative effectivenessEffectiveness studiesDatabase analysisStereotactic treatmentTreatmentPatientsLungTherapyProstateLiverBrain
2018
Impact of Health Insurance Status on Prostate Cancer Treatment Modality Selection in the United States
Bledsoe T, Park H, Rutter C, Aneja S, Nguyen PL, Yu J. Impact of Health Insurance Status on Prostate Cancer Treatment Modality Selection in the United States. American Journal Of Clinical Oncology 2018, 41: 1062-1068. PMID: 29521648, DOI: 10.1097/coc.0000000000000423.Peer-Reviewed Original ResearchTreatment modality selectionInsurance statusTreatment modalitiesProstate cancerPrivate insuranceProstate cancer treatment modalitiesMultivariable logistic regression analysisInvasive surgeryModality selectionCancer-directed treatmentD'Amico risk classificationTreatment modality choiceNational Cancer DatabaseLocalized prostate cancerPatient insurance statusExternal beam radiotherapyLogistic regression analysisHealth insurance statusStrongest predictorMen ages 18Cancer treatment modalitiesClinical factorsMultivariable analysisActive surveillanceCancer Database
2017
Point: Which Treatment Modality for Localized Prostate Cancer Yields Superior Quality of Life: Radiotherapy or Prostatectomy? Quality of Life is Better After Modern Radiotherapy Compared With Surgery.
Yu J, Hamstra D. Point: Which Treatment Modality for Localized Prostate Cancer Yields Superior Quality of Life: Radiotherapy or Prostatectomy? Quality of Life is Better After Modern Radiotherapy Compared With Surgery. Oncology 2017, 31: 830-2, 835. PMID: 29179251.Peer-Reviewed Original ResearchConceptsQuality of lifeSuperior quality of lifeModern radiotherapyTreatment modalitiesRadiotherapyProstatectomyProstateSurgery
2012
The influence of regional radiation oncologist and urologist capacities on treatment choice for prostate cancer management.
Yu J, Aneja S, Makarov D, Roberts K, Gross C. The influence of regional radiation oncologist and urologist capacities on treatment choice for prostate cancer management. Journal Of Clinical Oncology 2012, 30: 108-108. DOI: 10.1200/jco.2012.30.5_suppl.108.Peer-Reviewed Original ResearchHealth service areasOnly surgical treatmentSurgical treatmentHealth system characteristicsProstate cancer managementTreatment choiceCancer managementRadiation oncologistsRadiation oncologist densityEnd Results (SEER) databaseSeparate logistic regression modelsHealth system dataLogistic regression modelsArea Resource FileUse of RTUrologist densityHospital densityPatient factorsResults databaseSurgical interventionUrology serviceTreatment modalitiesProstate cancerNCI's SurveillanceRadiation therapy