2023
Risk of Squamous Cell Carcinoma of the Breast Following Postmastectomy Implant Reconstruction in Women With Breast Cancer and Carcinoma in Situ
Kinslow C, Yu J, DeStephano D, Kachnic L, Cheng S, Neugut A, Horowitz D. Risk of Squamous Cell Carcinoma of the Breast Following Postmastectomy Implant Reconstruction in Women With Breast Cancer and Carcinoma in Situ. JAMA Surgery 2023, 158: 769-771. PMID: 37074722, PMCID: PMC10116379, DOI: 10.1001/jamasurg.2023.0262.Peer-Reviewed Original Research
2022
Breast Cancer Subtypes and Incidence of Brain Metastases in the SEER Database
Kinslow C, Knisely J, Cheng S, Connolly E, Wang T, Yu J. Breast Cancer Subtypes and Incidence of Brain Metastases in the SEER Database. International Journal Of Radiation Oncology • Biology • Physics 2022, 114: e6. DOI: 10.1016/j.ijrobp.2022.07.685.Peer-Reviewed Original ResearchMetachronous brain metastasesSynchronous brain metastasesBreast cancer subtypesIncidence of brain metastasesBrain metastasesBreast cancerCancer subtypesTNBC patientsBreast cancer diagnosisFrequency of brain metastasesPresence of brain metastasesPrevalence of brain metastasesHER2+ breast cancerTime of initial diagnosisSubtypes of breast cancerIncreasing proportion of patientsOccult brain metastasesSEER-18 databaseBrain metastasis diagnosisMetastatic breast cancerProportion of patientsFrequency of subtypesBreast cancer patientsCancer diagnosisIdentifier number
2021
Prevalence of Missing Data in the National Cancer Database and Association With Overall Survival
Yang DX, Khera R, Miccio JA, Jairam V, Chang E, Yu JB, Park HS, Krumholz HM, Aneja S. Prevalence of Missing Data in the National Cancer Database and Association With Overall Survival. JAMA Network Open 2021, 4: e211793. PMID: 33755165, PMCID: PMC7988369, DOI: 10.1001/jamanetworkopen.2021.1793.Peer-Reviewed Original ResearchConceptsNational Cancer DatabaseNon-small cell lung cancerOverall survivalCell lung cancerCancer DatabaseMedical recordsLung cancerProstate cancerBreast cancerPatient recordsComplete dataRetrospective cohort studyCohort studyCancer RegistryCommon cancerVariables of interestHigh prevalenceMAIN OUTCOMEPatientsClinical advancementReal-world data sourcesCancerPrevalenceSurvivalHeterogeneous differences
2020
Physician trajectories of abandoning long‐course breast radiotherapy and their cost impact
Xu X, Soulos PR, Herrin J, Wang S, Pollack CE, Evans SB, Yu JB, Gross CP. Physician trajectories of abandoning long‐course breast radiotherapy and their cost impact. Health Services Research 2020, 56: 497-506. PMID: 33070305, PMCID: PMC8143683, DOI: 10.1111/1475-6773.13572.Peer-Reviewed Original ResearchConceptsPhysician peer groupsWhole breast irradiationCF-WBIRisk-adjusted ratesBreast radiotherapyPractice patternsLow useChronic Conditions Data WarehouseDistinct practice patternsPatients' clinical characteristicsSetting of radiotherapyAdjuvant breast radiotherapyYears of ageDistinct trajectoriesImportant cost implicationsHigher useAdjuvant radiotherapyClinical characteristicsEligible womenBreast cancerCost implicationsLatent class growth analysisService beneficiariesMedicare programRadiotherapyBeyond an Updated Graded Prognostic Assessment (Breast GPA): A Prognostic Index and Trends in Treatment and Survival in Breast Cancer Brain Metastases From 1985 to Today
Sperduto PW, Mesko S, Li J, Cagney D, Aizer A, Lin NU, Nesbit E, Kruser TJ, Chan J, Braunstein S, Lee J, Kirkpatrick JP, Breen W, Brown PD, Shi D, Shih HA, Soliman H, Sahgal A, Shanley R, Sperduto W, Lou E, Everett A, Boggs DH, Masucci L, Roberge D, Remick J, Plichta K, Buatti JM, Jain S, Gaspar LE, Wu CC, Wang TJC, Bryant J, Chuong M, Yu J, Chiang V, Nakano T, Aoyama H, Mehta MP. Beyond an Updated Graded Prognostic Assessment (Breast GPA): A Prognostic Index and Trends in Treatment and Survival in Breast Cancer Brain Metastases From 1985 to Today. International Journal Of Radiation Oncology • Biology • Physics 2020, 107: 334-343. PMID: 32084525, PMCID: PMC7276246, DOI: 10.1016/j.ijrobp.2020.01.051.Peer-Reviewed Original ResearchConceptsDiagnosis-specific prognostic factorsHuman epidermal receptor 2Prognostic factorsMedian survivalBreast-GPABrain metastasesBreast cancerCohort BCohort APrognostic indexReceptor 2Tumor subtypesBreast cancer brain metastasesKaplan-Meier survival estimatesCancer brain metastasesGraded Prognostic AssessmentKarnofsky performance statusLarge contemporary cohortLog-rank testFuture clinical trialsNew prognostic factorsGPA 0Extracranial metastasesPerformance statusBetter prognosis
2019
Abandonment trajectories of conventionally fractionated adjuvant radiotherapy in breast cancer care.
Xu X, Soulos P, Herrin J, Wang S, Pollack C, Evans S, Gross C, Yu J. Abandonment trajectories of conventionally fractionated adjuvant radiotherapy in breast cancer care. Journal Of Clinical Oncology 2019, 37: 531-531. DOI: 10.1200/jco.2019.37.15_suppl.531.Peer-Reviewed Original ResearchPhysician peer groupsBreast cancer careAdjuvant radiotherapyCancer careHigher useNational Medicare claimsPatient risk factorsDistinct trajectoriesYears of ageLow useDifferent baseline levelsRisk-adjusted ratesPatient cohortRisk factorsBreast cancerCost implicationsMedicare claimsBaseline levelsRadiotherapyMedicare perspectiveCFRTCurve analysisPhysiciansPatientsLatent growth curve analysisTumor subtype and other prognostic factors in breast cancer patients with brain metastases: The updated graded prognostic assessment (Breast-GPA).
Sperduto P, Mesko S, Cagney D, Nesbit E, Chan J, Lee J, Breen W, Shi D, Soliman H, Shanley R, Everett A, Masucci L, Remick J, Plichta K, Jain S, Wu C, Bryant J, Yu J, Nakano T, Mehta M. Tumor subtype and other prognostic factors in breast cancer patients with brain metastases: The updated graded prognostic assessment (Breast-GPA). Journal Of Clinical Oncology 2019, 37: 1079-1079. DOI: 10.1200/jco.2019.37.15_suppl.1079.Peer-Reviewed Original ResearchBrain metastasesPrognostic factorsMedian survivalTumor subtypesBreast cancer patientsBreast-GPAExtracranial metastasesCohort ALuminal BLuminal AImproved survivalCancer patientsComplication of breast cancerKaplan-Meier survival estimatesBrain radiation therapyLog-rank testRadiation therapyBasal tumorsPrognostic indexCohort BFatal complicationRetrospective databaseTreatment patternsPrognostic assessmentBreast cancerPV-0045 Is proton therapy a "pro" for breast cancer? A comparison of proton vs. non-proton RT using the NCDB
Chowdhary M, Lee A, Gao S, Barry P, Diaz R, Bagadiya N, Park H, Yu J, Wilson L, Moran M, Higgins S, Knowlton C, Patel K. PV-0045 Is proton therapy a "pro" for breast cancer? A comparison of proton vs. non-proton RT using the NCDB. Radiotherapy And Oncology 2019, 133: s15. DOI: 10.1016/s0167-8140(19)30465-7.Peer-Reviewed Original Research
2018
Persistent Use of Extended Fractionation Palliative Radiation Therapy for Medicare Beneficiaries with Metastatic Breast Cancer: 2011-2014
Yu J, Pollack C, Herrin J, Zhu W, Soulos P, Xu X, Gross C. Persistent Use of Extended Fractionation Palliative Radiation Therapy for Medicare Beneficiaries with Metastatic Breast Cancer: 2011-2014. International Journal Of Radiation Oncology • Biology • Physics 2018, 102: e425. DOI: 10.1016/j.ijrobp.2018.07.1241.Peer-Reviewed Original ResearchA review of recent advances in the management of breast cancer related pain
Zocca J, Valimahomed A, Yu J, Gulati A. A review of recent advances in the management of breast cancer related pain. Breast Cancer Management 2018, 7: bmt08. DOI: 10.2217/bmt-2018-0003.Peer-Reviewed Original ResearchCancer related painEffects of breast cancerIncidence of breast cancerRelated painBreast cancerDelivery of carePain syndromeInterventional pain managementPatient's functional statusPain reliefQuality of lifeSymptom managementPhysical therapyImprove painPain managementFunctional statusFascial plane blocksDeath ratePainLong-term effectsPlane blockTargeted therapyBreastCancerRehabilitation
2017
Discrepancies between biomarkers of primary breast cancer and subsequent brain metastases: an international multicenter study
Kaidar-Person O, Meattini I, Jain P, Bult P, Simone N, Kindts I, Steffens R, Weltens C, Navarria P, Belkacemi Y, Lopez-Guerra J, Livi L, Baumert B, Vieites B, Limon D, Kurman N, Ko K, Yu J, Chiang V, Poortmans P, Zagar T. Discrepancies between biomarkers of primary breast cancer and subsequent brain metastases: an international multicenter study. Breast Cancer Research And Treatment 2017, 167: 479-483. PMID: 28975433, DOI: 10.1007/s10549-017-4526-8.Peer-Reviewed Original ResearchConceptsBreast cancer patientsSubsequent brain metastasesHuman epidermal growth factor receptor 2Brain metastasesCancer patientsEthical research committeeReceptor statusPrimary tumorProgesterone receptorEstrogen receptorEpidermal growth factor receptor 2Triple-negative profileGrowth factor receptor 2Primary breast cancerPrimary breast tumorsInternational multicenter studyFactor receptor 2Multicenter studyAvailable histologyResultsA totalBreast cancerReceptor 2ConclusionsThe majorityPatientsBreast tumorsDiscrepancies Between Biological Markers of Primary Breast Cancer and Their Brain Metastases: An International Multicenter Study
Person O, Meattini I, Jain P, Bult P, Simone N, Kindts I, Steffens R, Weltens C, Navarria P, Belkacemi Y, Lopez J, Livi L, Baumert B, Vieites B, Limon D, Kurman N, Yu J, Chiang V, Poortmans P, Zagar T. Discrepancies Between Biological Markers of Primary Breast Cancer and Their Brain Metastases: An International Multicenter Study. International Journal Of Radiation Oncology • Biology • Physics 2017, 99: s170-s171. DOI: 10.1016/j.ijrobp.2017.06.431.Peer-Reviewed Original Research
2016
Modern Radiation Therapy for Left-Sided Breast Cancer: An Analysis of Mean Heart Dose Within Diverse Practice Settings
Hong J, Gross C, Shafman T, Hu X, Yu J, Ross R, Dosoretz A, Park H, Finkelstein S, Soulos P, Evans S. Modern Radiation Therapy for Left-Sided Breast Cancer: An Analysis of Mean Heart Dose Within Diverse Practice Settings. International Journal Of Radiation Oncology • Biology • Physics 2016, 96: s209. DOI: 10.1016/j.ijrobp.2016.06.520.Peer-Reviewed Original Research
2015
Secondary Myeloid Neoplasms in Older Women with Breast Cancer after Radiotherapy: A Population-Based Study
Zeidan A, Long J, Wang R, Yu J, Hall J, Abel G, Gore S, Gross C, Ma X, Davidoff A. Secondary Myeloid Neoplasms in Older Women with Breast Cancer after Radiotherapy: A Population-Based Study. Blood 2015, 126: 1676. DOI: 10.1182/blood.v126.23.1676.1676.Peer-Reviewed Original ResearchTherapy-related myeloid neoplasmsMDS/acute myeloid leukemiaSingle-modality radiotherapyAcute myeloid leukemiaBreast cancer patientsMonths of diagnosisEarly breast cancerCompeting-risk analysisMyelodysplastic syndromeBreast cancerCancer patientsBreast cancer diagnosisRisk factorsMyeloid neoplasmsRadiation therapyAML/myelodysplastic syndromeFemale breast cancer patientsNational Cancer Institute's SurveillanceRadiotherapy-treated patientsReceipt of radiotherapySecondary myeloid neoplasmsRetrospective cohort studyCancer diagnosisNumber of comorbiditiesBetter overall survivalTrends in Adjuvant and Neoadjuvant Radiotherapy for Cancer Treatment From 1973 to 2011
Le Bui D, Yu J. Trends in Adjuvant and Neoadjuvant Radiotherapy for Cancer Treatment From 1973 to 2011. The Cancer Journal 2015, 21: 147-149. PMID: 26049692, DOI: 10.1097/ppo.0000000000000114.Peer-Reviewed Original ResearchConceptsNeoadjuvant radiation therapyRadiation therapyThyroid cancerCervical cancerKidney cancerRadiation therapy useEnd Results databaseCancer-directed surgeryPercentage of patientsCoordinated careNeoadjuvant radiotherapyOral cavity/pharynxOvarian cancerProstate cancerResults databaseUterine cancerGenitourinary cancersOral cavityPancreatic cancerBladder cancerTherapy useMultidisciplinary clinical teamBreast cancerDisease sitesTherapy usage
2012
Short-term complications and use of breast brachytherapy in the national Medicare population in 2008-2009.
Presley C, Soulos P, Herrin J, Roberts K, Yu J, Killelea B, Lesnikoski B, Long J, Gross C. Short-term complications and use of breast brachytherapy in the national Medicare population in 2008-2009. Journal Of Clinical Oncology 2012, 30: 1030-1030. DOI: 10.1200/jco.2012.30.15_suppl.1030.Peer-Reviewed Original ResearchWhole breast irradiationHospital referral regionsBone complicationsClinical characteristicsSkin complicationsReferral regionsEarly-stage breast cancerNational treatment patternsOne-year overallReceipt of chemotherapyNumber of comorbiditiesShort-term complicationsDeep tissuesNational Medicare populationAdjuvant radiationComplication rateTreatment patternsDiagnosis codesBreast cancerMedicare claimsMedicare populationComplicationsMedicare beneficiariesTreatment groupsClinical practice