2018
Problem Drinking, Alcohol Expectancy, and Thalamic Resting-State Functional Connectivity in Nondependent Adult Drinkers
Zhornitsky S, Ide J, Wang W, Chao H, Zhang S, Hu S, Krystal J, Li C. Problem Drinking, Alcohol Expectancy, and Thalamic Resting-State Functional Connectivity in Nondependent Adult Drinkers. Brain Connectivity 2018, 8: 487-502. PMID: 30198312, PMCID: PMC6207153, DOI: 10.1089/brain.2018.0633.Peer-Reviewed Original ResearchConceptsAlcohol Use Disorders Identification TestResting-state functional connectivityThalamic connectivityCaudate connectivityFrontal associationThalamic dysfunctionCaudate headProblem drinkingWhole-brain linear regressionAE scoreSubcortical structuresFunctional connectivityBilateral caudate headRight caudate headDisorders Identification TestSex differencesThalamic subdivisionsThalamic subregionsParietal associationAlcohol misuseThalamusWhite matter tractographyAUDIT scoresNondependent drinkersAlcohol expectancies
2016
Clinically Anxious Individuals Show Disrupted Feedback between Inferior Frontal Gyrus and Prefrontal-Limbic Control Circuit
Cha J, DeDora D, Nedic S, Ide J, Greenberg T, Hajcak G, Mujica-Parodi L. Clinically Anxious Individuals Show Disrupted Feedback between Inferior Frontal Gyrus and Prefrontal-Limbic Control Circuit. Journal Of Neuroscience 2016, 36: 4708-4718. PMID: 27122030, PMCID: PMC6601720, DOI: 10.1523/jneurosci.1092-15.2016.Peer-Reviewed Original ResearchConceptsInferior frontal gyrusVentromedial prefrontal cortexFrontal gyrusPrefrontal-limbic regionsAnxious individualsStimulus meaningNeurobiological responsesPrefrontal cortexFear generalization taskPrefrontal-limbic circuitsPrefrontal-limbic connectivityEmotion regulationAffective neurosciencePrefrontal-limbic systemGeneralization taskPerceptual similaritySimilarity gradientsPrefrontal regionsFMRI studyClinical anxietyAnxiety spectrumAnxiety severityVmPFCFunctional connectivityGyrus