2010
Analgesic Effects of Ethanol Are Influenced by Family History of Alcoholism and Neuroticism
Ralevski E, Perrino A, Acampora G, Koretski J, Limoncelli D, Petrakis I. Analgesic Effects of Ethanol Are Influenced by Family History of Alcoholism and Neuroticism. Alcohol Clinical And Experimental Research 2010, 34: 1433-1441. PMID: 20497133, PMCID: PMC9136640, DOI: 10.1111/j.1530-0277.2010.01228.x.Peer-Reviewed Original ResearchConceptsFamily historyAnalgesic responseHigh N scoresAnalgesic effectNoxious electrical stimulationPositive family historyStart of infusionDoses of ethanolSeparate test daysNegative family historyTest dayExperience of painN scoreMore analgesiaPlacebo dayPain assessmentPersonality traitsIntravenous administrationHealthy subjectsEthanol challengeLow doseElectrical stimulationAlcoholismThirty-oneLow N scores
2008
Ethanol-like effects of thiopental and ketamine in healthy humans
Dickerson D, Pittman B, Ralevski E, Perrino A, Limoncelli D, Edgecombe J, Acampora G, Krystal J, Petrakis I. Ethanol-like effects of thiopental and ketamine in healthy humans. Journal Of Psychopharmacology 2008, 24: 203-211. PMID: 19028835, PMCID: PMC4484757, DOI: 10.1177/0269881108098612.Peer-Reviewed Original ResearchConceptsEthanol-like effectsEthanol-related effectsNMDA receptor antagonistBlock NMDA receptorsNMDA receptor antagonismSeparate test daysGamma-aminobutyric acidReceptor antagonismSubanesthetic dosesReceptor antagonistNMDA receptorsFamily historyEthanol intoxicationHealthy humansPharmacological agentsEthanol effectsKetamineReceptor activityReceptor functionLarger studyBehavioral effectsThiopentalIntoxicationSubjective intoxicationTest day