2023
Analysis of Drugs in Saliva of US Military Veterans Treated for Substance Use Disorders Using Supported Liquid Extraction and Surface-Enhanced Raman Spectral Analysis
Farquharson S, Shende C, Newcomb J, Petrakis I, Arias A. Analysis of Drugs in Saliva of US Military Veterans Treated for Substance Use Disorders Using Supported Liquid Extraction and Surface-Enhanced Raman Spectral Analysis. Molecules 2023, 28: 2010. PMID: 36903255, PMCID: PMC10004423, DOI: 10.3390/molecules28052010.Peer-Reviewed Original ResearchConceptsOpioid use disorderSubstance-related disordersUS military veteransUse disordersMilitary veteransDrug useIllicit drugsSubstance use disordersDrug overdose deathsIllicit drug useML of salivaBuprenorphine adherenceTreatment medicationsUrine testsOverdose deathsPatients' salivaDisease controlPatient samplesBuprenorphinePOC analyzerDrugsVulnerable populationsCare analyzerMedicationsDisorders
2019
Chapter 13 Trauma and Addiction—How to Treat Co-occurring PTSD and Substance Use Disorders
Vojvoda D, Petrakis I. Chapter 13 Trauma and Addiction—How to Treat Co-occurring PTSD and Substance Use Disorders. 2019, 189-196. DOI: 10.1016/b978-0-323-54856-4.00013-4.Peer-Reviewed Original ResearchSubstance use disordersAlcohol use disorderPosttraumatic stress disorderComorbid substance use disorderPTSD symptomsCo-occurring posttraumatic stress disorderRandomized clinical studyWorse clinical outcomesTreatment of patientsSeverity of AUDSeverity of symptomsCo-occurring disordersReduction of severityRecent pharmacological advancesAnticonvulsant topiramateClinical outcomesPharmacological treatmentPTSD comorbidityClinical studiesPharmacological advancesInconstant effectsMedicationsUse disordersAlcohol consumptionN-acetylcysteine
2013
Chapter 38 Disulfiram for Alcohol and Other Drug Use
Kerfoot K, Petrakis I. Chapter 38 Disulfiram for Alcohol and Other Drug Use. 2013, 367-374. DOI: 10.1016/b978-0-12-398338-1.00038-5.Peer-Reviewed Original ResearchUse disordersEfficacy of disulfiramAlcohol use disorderClinical research studiesCocaine use disorderDisulfiram useFirst medicationCardiorespiratory collapseIngested alcoholRare caseDrug AdministrationUS FoodDrug useAlcohol dependenceAddiction treatmentDisulfiramTreatmentNormal metabolismDisordersPositive outcomesPotential usefulnessNauseaMedicationsHeadacheAdministration
2010
Sedative-Hypnotics and Anxiolytics
Arnaout B, Petrakis I. Sedative-Hypnotics and Anxiolytics. 2010, 511-523. DOI: 10.1007/978-1-4419-0338-9_23.Peer-Reviewed Original ResearchCentral nervous system depressantsPsychiatric adverse eventsGroup of medicationsNon-benzodiazepine hypnoticsNon-medical useAdverse eventsSexual dysfunctionSleep disordersSedative hypnoticsPsychotic manifestationsCognitive disordersTherapeutic valueGeneral medicineAnxiety disordersMedicationsDisordersAnxiolyticsDeleterious effectsAbuseHypnoticsDysfunctionBenzodiazepinesEpidemiologyIntoxicationNeurology
2005
Setting Up a Buprenorphine Clinic
Balachandra K, Petrakis I. Setting Up a Buprenorphine Clinic. Addictive Disorders & Their Treatment 2005, 4: 111-116. DOI: 10.1097/01.adt.0000163701.68367.95.Peer-Reviewed Original ResearchBuprenorphine clinicOutpatient substance abuse clinicsSpectrum of treatmentOne-year experienceSubstance abuse clinicsOpioid dependencePharmacotherapeutic optionsOutpatient settingTreatment challengesOpioid addictionHospital settingClinicNew FDABuprenorphinePatientsMedicationsPositive experiencesSetting
1999
Toward a rational pharmacotherapy of comorbid substance abuse in schizophrenic patients
Krystal J, D'Souza D, Madonick S, Petrakis I. Toward a rational pharmacotherapy of comorbid substance abuse in schizophrenic patients. Schizophrenia Research 1999, 35: s35-s49. PMID: 10190224, DOI: 10.1016/s0920-9964(98)00162-5.Peer-Reviewed Original ResearchConceptsSchizophrenic patientsSubstance abuseTerms of rehospitalizationComorbid substance abuseExacerbation of symptomsHealth care expensesSelf-medication hypothesisBetter prognosisMedical illnessPharmacotherapeutic approachesRational pharmacotherapyNonschizophrenic populationsPatientsVocational functionIllicit substancesCare expensesAbuseVulnerability hypothesisRehospitalizationExacerbationMedicationsPharmacotherapyPrognosisPsychostimulantsIllness