Association of Renin-Angiotensin-Aldosterone System Inhibitor Usage Patterns with Midterm Amputation-Free Survival after Lower Extremity Bypass for Peripheral Arterial Disease
Naazie I, Arhuidese I, Abdelgawwad M, Unkart J, Conte M, Malas M. Association of Renin-Angiotensin-Aldosterone System Inhibitor Usage Patterns with Midterm Amputation-Free Survival after Lower Extremity Bypass for Peripheral Arterial Disease. Annals Of Vascular Surgery 2022, 88: 79-89. PMID: 36028182, DOI: 10.1016/j.avsg.2022.07.022.Peer-Reviewed Original ResearchMeSH KeywordsAgedAldosteroneHumansLower ExtremityMedicarePeripheral Arterial DiseaseRenin-Angiotensin SystemRetrospective StudiesRisk FactorsTreatment OutcomeUnited StatesConceptsRenin-angiotensin-aldosterone system inhibitor useRenin-angiotensin-aldosterone system inhibitorsLower extremity bypassAmputation-free survivalPeripheral arterial diseaseArtery diseaseAssociated with improved 30-day mortalityAssociated with improved survivalAssociated with 2.8-foldPeripheral arterial disease patientsLEB outcomesArtery disease patientsLower-extremity bypassSurvival benefitSystem inhibitorsPostoperative periodRAAS inhibitionStudy cohortCox regressionPrimary outcomePotential confoundersIncreased oddsDisease patientsPatientsMortality