2022
Association of Renin-Angiotensin-Aldosterone System Inhibitor Usage Patterns with Midterm Amputation-Free Survival after Lower Extremity Bypass for Peripheral Arterial Disease
Naazie I, Arhuidese I, Abdelgawwad M, Unkart J, Conte M, Malas M. Association of Renin-Angiotensin-Aldosterone System Inhibitor Usage Patterns with Midterm Amputation-Free Survival after Lower Extremity Bypass for Peripheral Arterial Disease. Annals Of Vascular Surgery 2022, 88: 79-89. PMID: 36028182, DOI: 10.1016/j.avsg.2022.07.022.Peer-Reviewed Original ResearchConceptsRenin-angiotensin-aldosterone system inhibitor useRenin-angiotensin-aldosterone system inhibitorsLower extremity bypassAmputation-free survivalPeripheral arterial diseaseArtery diseaseAssociated with improved 30-day mortalityAssociated with improved survivalAssociated with 2.8-foldPeripheral arterial disease patientsLEB outcomesArtery disease patientsLower-extremity bypassSurvival benefitSystem inhibitorsPostoperative periodRAAS inhibitionStudy cohortCox regressionPrimary outcomePotential confoundersIncreased oddsDisease patientsPatientsMortality
2015
Vascular access modifies the protective effect of obesity on survival in hemodialysis patients
Arhuidese I, Obeid T, Hicks C, Qazi U, Botchey I, Zarkowsky D, Reifsnyder T, Malas M. Vascular access modifies the protective effect of obesity on survival in hemodialysis patients. Surgery 2015, 158: 1628-1634. PMID: 26126794, DOI: 10.1016/j.surg.2015.04.036.Peer-Reviewed Original ResearchConceptsBody mass indexEnd-stage renal diseaseNormal body mass indexProtective effect of obesityHigher body mass indexEffect of obesityObesity paradoxProtective effect of increasing BMIEffect of increased BMIBody mass index statusMass indexHD accessProtective effectAssociated with lower mortalityPropensity score matching analysisSurvival of patientsScore matching analysisSurvival benefitImproved survivalRetrospective studyHemodialysis accessInitiate hemodialysisPatient backgroundRenal diseaseCox regressionTrends in Incident Hemodialysis Access and Mortality
Malas MB, Canner JK, Hicks CW, Arhuidese IJ, Zarkowsky DS, Qazi U, Schneider EB, Black JH, Segev DL, Freischlag JA. Trends in Incident Hemodialysis Access and Mortality. JAMA Surgery 2015, 150: 441-448. PMID: 25738981, DOI: 10.1001/jamasurg.2014.3484.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseaseHemodialysis cathetersArteriovenous fistulaArteriovenous graftsLower mortalityRenal diseaseVascular accessHD outcomesNational Kidney Foundation Kidney Disease Outcomes Quality InitiativeKidney Foundation Kidney Disease Outcomes Quality InitiativeMultivariable Cox proportional hazards modelsPrior renal replacement therapyUS Renal Data SystemCox proportional hazards modelArteriovenous fistula useIncident HD patientsInitiation of hemodialysisRetrospective cohort studyRenal replacement therapyProportional hazards modelFistula useCohort studySurvival benefitHD patientsPropensity score-matching technique