2022
Association of Renin-Angiotensin-Aldosterone System Inhibitor Usage Patterns with Midterm Amputation-Free Survival after Lower Extremity Bypass for Peripheral Arterial Disease
Naazie I, Arhuidese I, Abdelgawwad M, Unkart J, Conte M, Malas M. Association of Renin-Angiotensin-Aldosterone System Inhibitor Usage Patterns with Midterm Amputation-Free Survival after Lower Extremity Bypass for Peripheral Arterial Disease. Annals Of Vascular Surgery 2022, 88: 79-89. PMID: 36028182, DOI: 10.1016/j.avsg.2022.07.022.Peer-Reviewed Original ResearchConceptsRenin-angiotensin-aldosterone system inhibitor useRenin-angiotensin-aldosterone system inhibitorsLower extremity bypassAmputation-free survivalPeripheral arterial diseaseArtery diseaseAssociated with improved 30-day mortalityAssociated with improved survivalAssociated with 2.8-foldPeripheral arterial disease patientsLEB outcomesArtery disease patientsLower-extremity bypassSurvival benefitSystem inhibitorsPostoperative periodRAAS inhibitionStudy cohortCox regressionPrimary outcomePotential confoundersIncreased oddsDisease patientsPatientsMortality
2019
Outcomes of Infrainguinal Lower Extremity Bypass Are Superior in Kidney Transplant Recipients Than Patients with Dialysis
Nejim B, Hicks C, Arhuidese I, Locham S, Dakour-Aridi H, Malas M. Outcomes of Infrainguinal Lower Extremity Bypass Are Superior in Kidney Transplant Recipients Than Patients with Dialysis. Annals Of Vascular Surgery 2019, 63: 209-217. PMID: 31349053, DOI: 10.1016/j.avsg.2019.04.026.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmputation, SurgicalBlood Vessel Prosthesis ImplantationDatabases, FactualFemaleHumansKidney Failure, ChronicKidney TransplantationLimb SalvageLower ExtremityMaleMiddle AgedPeripheral Arterial DiseaseProgression-Free SurvivalRenal DialysisRetrospective StudiesRisk FactorsSaphenous VeinTime FactorsVascular PatencyConceptsLower extremity bypassEnd-stage renal diseaseKT recipientsPrimary patencyDialysis therapyAmputation-free survivalKidney transplantationVascular Quality Initiative databaseRisk-adjusted hazardsKidney transplant recipientsPositive effects of KTRisk of mortalityEffects of KTRisk of amputationLower-extremity bypassSurgical outcomesTransplant recipientsBaseline characteristicsBypass proceduresDialysis patientsRenal diseaseComparative efficacyKT groupDT groupPatients
2017
Regional variation in the cost of infrainguinal lower extremity bypass surgery in the United States
Nejim B, Wang S, Arhuidese I, Obeid T, Alshaikh H, Aridi H, Locham S, Malas M. Regional variation in the cost of infrainguinal lower extremity bypass surgery in the United States. Journal Of Vascular Surgery 2017, 67: 1170-1180.e4. PMID: 29074114, DOI: 10.1016/j.jvs.2017.08.055.Peer-Reviewed Original ResearchMeSH KeywordsAgedChi-Square DistributionCost-Benefit AnalysisDatabases, FactualFemaleHealth ExpendituresHealthcare DisparitiesHospital CostsHumansLinear ModelsLower ExtremityMaleMiddle AgedModels, EconomicPeripheral Arterial DiseasePractice Patterns, Physicians'Process Assessment, Health CareRetrospective StudiesSurgeonsTreatment OutcomeUnited StatesVascular GraftingConceptsLower extremity bypassIn-hospital costsHospital factorsService-specific costsInfrainguinal lower extremity bypassHealth care expendituresMedian in-hospital costsGeneralized linear regression modelsLower extremity bypass surgeryHealth systemPeripheral arterial diseaseStandard revascularization proceduresPatient's clinical conditionIdentified adult patientsLinear regression modelsCare expendituresFinancial burdenRegional variationMedian costPatient demographicsClinical characteristicsAdult patientsBypass surgeryNortheast regionPatient characteristicsLong-term outcomes after autogenous versus synthetic lower extremity bypass in patients on hemodialysis
Arhuidese I, Hicks C, Locham S, Obeid T, Nejim B, Malas M. Long-term outcomes after autogenous versus synthetic lower extremity bypass in patients on hemodialysis. Surgery 2017, 162: 1071-1079. PMID: 28712733, DOI: 10.1016/j.surg.2017.04.026.Peer-Reviewed Original ResearchConceptsLong-term outcomesBypass operationProsthetic conduitHemodialysis patientsAutogenous conduitLimb salvageHigh-risk population of patientsEvaluate long-term outcomesCohort of hemodialysis patientsPrimary-assisted patencyFemoral-tibialType of bypassCox regression analysisLower extremity bypassPopulation of patientsUnited States Renal Data SystemHigh-risk populationPatient's life expectancyPopulation-based cohortCritical limb ischemiaPopliteal-tibial bypassSecondary patencyPrimary patencyConduit optionsPostoperative outcomes
2016
Outcomes after open infrainguinal bypass in patients with scleroderma
Arhuidese I, Malas M, Obeid T, Massada K, Khaled A, Alzahrani A, Samaha G, Reifsnyder T. Outcomes after open infrainguinal bypass in patients with scleroderma. Journal Of Vascular Surgery 2016, 64: 117-123. PMID: 27005756, DOI: 10.1016/j.jvs.2015.12.057.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAutograftsBaltimoreCritical IllnessFemaleGraft SurvivalHumansIschemiaKaplan-Meier EstimateLimb SalvageLower ExtremityMaleMiddle AgedMultivariate AnalysisPeripheral Arterial DiseaseProportional Hazards ModelsRetrospective StudiesRisk FactorsSaphenous VeinScleroderma, SystemicSeverity of Illness IndexTime FactorsTreatment OutcomeVascular GraftingVascular PatencyConceptsInfrainguinal bypass surgeryLong-term outcomesBypass surgerySystemic sclerosisGraft failureSociety for Vascular Surgery standardsScleroderma patientsArtery diseaseFollow-up durationStandard deviation ageCox regression analysisSevere peripheral arterial diseaseHistory of hypertensionLower extremity bypassCoronary artery diseaseLimb salvage rateCritical limb ischemiaPeripheral arterial diseaseDeviation ageReporting of outcomesKaplan-MeierPoor outcomeSalvage rateInfrainguinal bypassLimb ischemia