2012
A Dual Role of Evi-1 During Developmental Hematopoiesis
Konantz M, Grauer M, Grzywna S, Park I, Daley G, Kanz L, Lengerke C. A Dual Role of Evi-1 During Developmental Hematopoiesis. Blood 2012, 120: 765. DOI: 10.1182/blood.v120.21.765.765.Peer-Reviewed Original ResearchEvi-1Developmental hematopoiesisZebrafish embryosSCL expressionProgenitor cellsHematopoietic cellsPre-mRNA splicingHuman hematopoietic developmentEvi-1 locusMurine hematopoietic cellsHuman iPS cellsPrecise molecular basisSurvival/proliferationEmbryonic myelopoiesisPluripotent stem cellsEvi-1 expressionErythroid progenitor cellsDefinitive hematopoiesisPrimitive erythroid progenitor cellsPrimitive erythropoiesisZebrafish zygotesHSC formationPrimitive hematopoiesisBlood developmentSitu hybridization analysis
2011
Evi-1 Regulates Myelopoiesis and Hematopoietic Stem Cell Development in Zebrafish and Human Pluripotent Stem Cells
Konantz M, Grauer M, Grzywna S, Brugman M, Kanz L, Park I, Daley G, Baum C, Lengerke C. Evi-1 Regulates Myelopoiesis and Hematopoietic Stem Cell Development in Zebrafish and Human Pluripotent Stem Cells. Blood 2011, 118: 1281. DOI: 10.1182/blood.v118.21.1281.1281.Peer-Reviewed Original ResearchHuman pluripotent stem cellsPluripotent stem cellsEvi-1Developmental hematopoiesisZebrafish embryosHematopoietic developmentHematopoietic stem cellsStem cellsPosterior lateral plate mesodermHematopoietic stem cell developmentPosterior blood islandHuman developmental hematopoiesisLateral plate mesodermStem cell developmentPre-mRNA splicingEvi-1 locusDays post fertilizationHematopoietic stem cell proliferationMurine hematopoietic cellsStem cell proliferationExpression of PUEmbryonic myelopoiesisEvi-1 expressionErythroid progenitor cellsPrimitive erythroid progenitor cells
2009
Hematopoietic Development From Human Induced Pluripotent Stem Cells.
Grauer M, Konantz M, Niebuhr N, Kanz L, Park I, Daley G, Lengerke C. Hematopoietic Development From Human Induced Pluripotent Stem Cells. Blood 2009, 114: 2530. DOI: 10.1182/blood.v114.22.2530.2530.Peer-Reviewed Original ResearchMouse embryonic stem cellsEmbryonic stem cellsInduced pluripotent stem cellsPluripotent stem cellsHuman embryonic stem cellsHematopoietic stem cellsHuman induced pluripotent stem cellsHuman iPS cellsIPS cellsCdx genesHematopoietic developmentBlood lineagesStem cellsBlood formationEmbryonic blood formationGenetic modificationHuman developmental hematopoiesisDifferentiated somatic cellsHuman pluripotent stem cell linesStem cell linesIrradiated adult micePluripotent stem cell lineDevelopmental hematopoiesisHematopoietic genesHox genes