2016
Bisphenol A Impairs Mature Sperm Functions by a CatSper-Relevant Mechanism
Wang H, Liu M, Li N, Luo T, Zheng L, Zeng X. Bisphenol A Impairs Mature Sperm Functions by a CatSper-Relevant Mechanism. Toxicological Sciences 2016, 152: 145-154. PMID: 27125968, DOI: 10.1093/toxsci/kfw070.Peer-Reviewed Original ResearchConceptsToxicity of BPANormal mouse spermSperm functionMature sperm functionVivo administrationEndocrine-disrupting chemicalsWestern blotDifferent dosesSignificant decreaseSperm total motilitySignificant reductionBisphenol AMiceSperm motilityMouse spermMouse spermatozoaMotilityCatSperTotal motilityToxicity
2013
Sperm-specific ion channels: targets holding the most potential for male contraceptives in development
Zheng L, Wang H, Li B, Zeng X. Sperm-specific ion channels: targets holding the most potential for male contraceptives in development. Contraception 2013, 88: 485-491. PMID: 23845210, DOI: 10.1016/j.contraception.2013.06.002.Peer-Reviewed Original ResearchMeSH KeywordsAnoctamin-1Calcium ChannelsChloride Channel AgonistsChloride ChannelsContraceptive Agents, MaleDrugs, InvestigationalHumansIon ChannelsLarge-Conductance Calcium-Activated Potassium Channel alpha SubunitsLarge-Conductance Calcium-Activated Potassium ChannelsMaleMembrane ProteinsNeoplasm ProteinsOrgan SpecificityPotassium Channels, Voltage-GatedProtein SubunitsSignal TransductionSpermatozoa