2023
Prediction of Brain Metastases Development in Patients With Lung Cancer by Explainable Artificial Intelligence From Electronic Health Records.
Li Z, Li R, Zhou Y, Rasmy L, Zhi D, Zhu P, Dono A, Jiang X, Xu H, Esquenazi Y, Zheng W. Prediction of Brain Metastases Development in Patients With Lung Cancer by Explainable Artificial Intelligence From Electronic Health Records. JCO Clinical Cancer Informatics 2023, 7: e2200141. PMID: 37018650, PMCID: PMC10281421, DOI: 10.1200/cci.22.00141.Peer-Reviewed Original ResearchConceptsBrain metastasesExplainable artificial intelligenceFeature attribution methodsLung cancerEHR dataArtificial intelligenceCerner Health Facts databaseBM developmentExplainable artificial intelligence approachBrain metastasis developmentHealth Facts databaseElectronic health record dataRecurrent neural network modelArtificial intelligence approachHealth record dataModel decision processStructured EHR dataNeural network modelDecision processAttribution methodsHigh-quality cohortElectronic health recordsPrompt treatmentMetastasis developmentIntelligence approach
2022
Recurrent neural network models (CovRNN) for predicting outcomes of patients with COVID-19 on admission to hospital: model development and validation using electronic health record data
Rasmy L, Nigo M, Kannadath B, Xie Z, Mao B, Patel K, Zhou Y, Zhang W, Ross A, Xu H, Zhi D. Recurrent neural network models (CovRNN) for predicting outcomes of patients with COVID-19 on admission to hospital: model development and validation using electronic health record data. The Lancet Digital Health 2022, 4: e415-e425. PMID: 35466079, PMCID: PMC9023005, DOI: 10.1016/s2589-7500(22)00049-8.Peer-Reviewed Original ResearchConceptsLight Gradient Boost MachineFeature engineeringGradient-boosting machineMultiple machine learning modelsElectronic health record dataNeural network-based modelReal-world datasetsRecurrent neural network modelComplex feature engineeringMachine learning modelsBinary classification taskSpecific feature selectionLogistic regression algorithmNeural network modelHealth record dataRecurrent neural network-based modelBinary classification modelNetwork-based modelTraditional machineExtensive data preprocessingHigh prediction accuracyMultiple external datasetsClassification taskData preprocessingFeature selection
2020
Asthma Exacerbation Prediction and Risk Factor Analysis Based on a Time-Sensitive, Attentive Neural Network: Retrospective Cohort Study
Xiang Y, Ji H, Zhou Y, Li F, Du J, Rasmy L, Wu S, Zheng W, Xu H, Zhi D, Zhang Y, Tao C. Asthma Exacerbation Prediction and Risk Factor Analysis Based on a Time-Sensitive, Attentive Neural Network: Retrospective Cohort Study. Journal Of Medical Internet Research 2020, 22: e16981. PMID: 32735224, PMCID: PMC7428917, DOI: 10.2196/16981.Peer-Reviewed Original ResearchConceptsAttentive Neural NetworkAsthma exacerbationsRisk factorsNeural networkAdvanced deep learning modelsClinical variablesDeep learning modelsCerner Health Facts databaseLarge electronic health recordNeural network modelRetrospective cohort studyHealth Facts databasePotential risk factorsRisk factor analysisPersonalized risk factorsElectronic health recordsBaseline methodsLearning modelPersonalized risk scoreProgressive asthmaAsthma symptomsEsophageal refluxAdult patientsCohort studyTime-Sensitive
2019
Temporal indexing of medical entity in Chinese clinical notes
Liu Z, Wang X, Chen Q, Tang B, Xu H. Temporal indexing of medical entity in Chinese clinical notes. BMC Medical Informatics And Decision Making 2019, 19: 17. PMID: 30700331, PMCID: PMC6354334, DOI: 10.1186/s12911-019-0735-x.Peer-Reviewed Original ResearchConceptsSupport vector machineConvolutional neural networkTemporal indexingNeural network modelIndexing taskRelation classificationMedical entitiesRecurrent convolutional neural network modelMachine learning-based systemsConvolutional neural network modelDeep neural network modelNetwork methodNetwork modelLearning-based systemTemporal relation classificationRecurrent neural network methodChinese clinical notesTemporal relationsClinical notesNeural network methodI2b2 NLP challengeContext informationTime indexingSemantic informationBaseline methods