2021
Privacy-preserving genotype imputation in a trusted execution environment
Dokmai N, Kockan C, Zhu K, Wang X, Sahinalp S, Cho H. Privacy-preserving genotype imputation in a trusted execution environment. Cell Systems 2021, 12: 983-993.e7. PMID: 34450045, PMCID: PMC8542641, DOI: 10.1016/j.cels.2021.08.001.Peer-Reviewed Original ResearchConceptsTrusted Execution EnvironmentExecution environmentHardware-based solutionsSide-channel attacksIntel SGXEnhanced securityPrivacy concernsAnalysis servicesImputation ServerServer limitData resourcesImputation algorithmSGXServerImputation softwareGenomic data resourcesImputation accuracyGenotype imputationImputation strategiesServicesDownstream analysisScalabilityImputationEssential toolSecurity
2020
Mechanisms for Hiding Sensitive Genotypes with Information-Theoretic Privacy
Ye F, Cho H, Rouayheb S. Mechanisms for Hiding Sensitive Genotypes with Information-Theoretic Privacy. 2020, 00: 902-907. DOI: 10.1109/isit44484.2020.9174492.Peer-Reviewed Original ResearchInformation-theoretic privacyGenomic data sharingCritical health-related informationEfficient algorithmic implementationHidden Markov ModelPersonal genomics servicesData sharingGenomic privacyPrivacyAlgorithmic implementationSuch servicesHealth-related informationStraightforward solutionMarkov modelGenomic dataServicesGenomic servicesInformationSharingImplementationCorrelation structureData