2023
Assessing transcriptomic reidentification risks using discriminative sequence models
Sadhuka S, Fridman D, Berger B, Cho H. Assessing transcriptomic reidentification risks using discriminative sequence models. Genome Research 2023, 33: 1101-1112. PMID: 37541758, PMCID: PMC10538488, DOI: 10.1101/gr.277699.123.Peer-Reviewed Original ResearchConceptsExpression quantitative trait lociGene expression dataExpression dataQuantitative trait lociOmics data setsGene expression profilesTrait lociGenomic regionsGenetic variationGene expressionExpression profilesMolecular insightsLinkage disequilibriumFunctional impactGenotypesTranscriptomicsLociSame individualDisequilibriumSequenceExpressionPrevious studiesFull extentData sets
2016
Reconstructing Causal Biological Networks through Active Learning
Cho H, Berger B, Peng J. Reconstructing Causal Biological Networks through Active Learning. PLOS ONE 2016, 11: e0150611. PMID: 26930205, PMCID: PMC4773135, DOI: 10.1371/journal.pone.0150611.Peer-Reviewed Original ResearchConceptsGaussian Bayesian networksBayesian networkContinuous Bayesian networksDiscrete Bayesian networksBiological networksFast convergenceGreat practical interestGene regulatory networksGraph structurePractical interestQuantitative propertiesSignificant runtime improvementsComplex biological systemsRuntime improvementCausal biological networksSystems biologyCentral problemFinal distributionPrevious approachesNetwork structureResource constraintsData setsLearning algorithmImportant modelActive learning algorithm