2023
Concurrent Validity and Reliability of Suicide Risk Assessment Instruments: A Meta-Analysis of 20 Instruments Across 27 International Cohorts
Campos A, Van Velzen L, Veltman D, Pozzi E, Ambrogi S, Ballard E, Banaj N, Başgöze Z, Bellow S, Benedetti F, Bollettini I, Brosch K, Canales-Rodríguez E, Clarke-Rubright E, Colic L, Connolly C, Courtet P, Cullen K, Dannlowski U, Dauvermann M, Davey C, Deverdun J, Dohm K, Erwin-Grabner T, Goya-Maldonado R, Fani N, Fortea L, Fuentes-Claramonte P, Gonul A, Gotlib I, Grotegerd D, Harris M, Harrison B, Haswell C, Hawkins E, Hill D, Hirano Y, Ho T, Jollant F, Jovanovic T, Kircher T, Klimes-Dougan B, le Bars E, Lochner C, McIntosh A, Meinert S, Mekawi Y, Melloni E, Mitchell P, Morey R, Nakagawa A, Nenadić I, Olié E, Pereira F, Phillips R, Piras F, Poletti S, Pomarol-Clotet E, Radua J, Ressler K, Roberts G, Rodriguez-Cano E, Sacchet M, Salvador R, Sandu A, Shimizu E, Singh A, Spalletta G, Steele J, Stein D, Stein F, Stevens J, Teresi G, Uyar-Demir A, van der Wee N, van der Werff S, van Rooij S, Vecchio D, Verdolini N, Vieta E, Waiter G, Whalley H, Whittle S, Yang T, Zarate C, Thompson P, Jahanshad N, van Harmelen A, Blumberg H, Schmaal L, Rentería M. Concurrent Validity and Reliability of Suicide Risk Assessment Instruments: A Meta-Analysis of 20 Instruments Across 27 International Cohorts. Neuropsychology 2023, 37: 315-329. PMID: 37011159, PMCID: PMC10132776, DOI: 10.1037/neu0000850.Peer-Reviewed Original Research
2022
Elevated cognitive rumination and adverse life events are associated with lower cortical surface area and suicidal ideation in adolescents with major depressive disorder
Dauvermann M, Schmaal L, Colic L, van Velzen L, Bellow S, Ford T, Suckling J, Goodyer I, Consortium I, Blumberg H, van Harmelen A. Elevated cognitive rumination and adverse life events are associated with lower cortical surface area and suicidal ideation in adolescents with major depressive disorder. Journal Of Affective Disorders 2022, 325: 93-101. PMID: 36584707, DOI: 10.1016/j.jad.2022.12.087.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentDepressive Disorder, MajorHumansRisk FactorsRumination, CognitiveSuicidal IdeationSuicide, AttemptedConceptsMajor depressive disorderStructural brain alterations associated with suicidal thoughts and behaviors in young people: results from 21 international studies from the ENIGMA Suicidal Thoughts and Behaviours consortium
van Velzen LS, Dauvermann MR, Colic L, Villa LM, Savage HS, Toenders YJ, Zhu AH, Bright JK, Campos AI, Salminen LE, Ambrogi S, Ayesa-Arriola R, Banaj N, Başgöze Z, Bauer J, Blair K, Blair RJ, Brosch K, Cheng Y, Colle R, Connolly CG, Corruble E, Couvy-Duchesne B, Crespo-Facorro B, Cullen KR, Dannlowski U, Davey CG, Dohm K, Fullerton JM, Gonul AS, Gotlib IH, Grotegerd D, Hahn T, Harrison BJ, He M, Hickie IB, Ho TC, Iorfino F, Jansen A, Jollant F, Kircher T, Klimes-Dougan B, Klug M, Leehr EJ, Lippard ETC, McLaughlin KA, Meinert S, Miller AB, Mitchell PB, Mwangi B, Nenadić I, Ojha A, Overs BJ, Pfarr JK, Piras F, Ringwald KG, Roberts G, Romer G, Sanches M, Sheridan MA, Soares JC, Spalletta G, Stein F, Teresi GI, Tordesillas-Gutiérrez D, Uyar-Demir A, van der Wee NJA, van der Werff SJ, Vermeiren RRJM, Winter A, Wu MJ, Yang TT, Thompson PM, Rentería ME, Jahanshad N, Blumberg HP, van Harmelen AL, Schmaal L. Structural brain alterations associated with suicidal thoughts and behaviors in young people: results from 21 international studies from the ENIGMA Suicidal Thoughts and Behaviours consortium. Molecular Psychiatry 2022, 27: 4550-4560. PMID: 36071108, PMCID: PMC9734039, DOI: 10.1038/s41380-022-01734-0.Peer-Reviewed Original ResearchConceptsMood disordersSuicidal thoughtsSuicide attemptsBrain alterationsMRI metricsSuicidal ideationColumbia-Suicide Severity Rating ScaleStructural brain alterationsLifetime suicide attemptsSeverity Rating ScaleCurrent suicidal ideationActual suicide attemptsHealthy controlsAssessment instrumentsClinical controlEarly interventionMental disordersSignificant associationFrontal poleBrain morphologySuicide riskSuicide attemptersRating ScaleYoung peopleDisorders
2020
Imaging suicidal thoughts and behavior: the promise of computational models
van Harmelen AL, Schmaal L, Blumberg HP. Imaging suicidal thoughts and behavior: the promise of computational models. Neuropsychopharmacology 2020, 46: 219-220. PMID: 32895454, PMCID: PMC7688630, DOI: 10.1038/s41386-020-00841-2.Peer-Reviewed Original Research
2019
Imaging suicidal thoughts and behaviors: a comprehensive review of 2 decades of neuroimaging studies
Schmaal L, van Harmelen AL, Chatzi V, Lippard ETC, Toenders YJ, Averill LA, Mazure CM, Blumberg HP. Imaging suicidal thoughts and behaviors: a comprehensive review of 2 decades of neuroimaging studies. Molecular Psychiatry 2019, 25: 408-427. PMID: 31787757, PMCID: PMC6974434, DOI: 10.1038/s41380-019-0587-x.Peer-Reviewed Original ResearchMeSH KeywordsBrainEmotionsFemaleGyrus CinguliHumansMaleMental DisordersNeuroimagingPrefrontal CortexSuicidal IdeationSuicideSuicide, AttemptedConceptsVentral prefrontal cortexSuicidal ideationSuicidal thoughtsDorsal PFCDorsal anterior cingulate cortexAnterior cingulate cortexHigh-risk circumstancesBrain alterationsBrain areasLarger sample sizeCingulate cortexMolecular alterationsMental disordersNarrative reviewSuicide thoughtsPrefrontal cortexNeurobiological substratesInhibition of behaviorSuicide attempt behaviorBrain systemsCortexInsulaImpairmentComprehensive reviewLongitudinal design
2018
Preliminary examination of gray and white matter structure and longitudinal structural changes in frontal systems associated with future suicide attempts in adolescents and young adults with mood disorders
Lippard ETC, Johnston JAY, Spencer L, Quatrano S, Fan S, Sankar A, Weathers J, Pittman B, Oquendo MA, Blumberg HP. Preliminary examination of gray and white matter structure and longitudinal structural changes in frontal systems associated with future suicide attempts in adolescents and young adults with mood disorders. Journal Of Affective Disorders 2018, 245: 1139-1148. PMID: 30699858, PMCID: PMC6487887, DOI: 10.1016/j.jad.2018.11.097.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAnisotropyBipolar DisorderCross-Sectional StudiesDepressive Disorder, MajorDiffusion Tensor ImagingFemaleFrontal LobeGray MatterGyrus CinguliHumansInternal CapsuleMagnetic Resonance ImagingMaleMood DisordersPrefrontal CortexSuicidal IdeationSuicide, AttemptedWhite MatterYoung AdultConceptsMood disordersGray matter volumeLongitudinal structural changesSuicide-related behaviorsFuture suicide attemptsFractional anisotropyWhite matter structuresMatter volumeWhite matterSuicide attemptsHigh-resolution structural magnetic resonance imagingYoung adultsWhite matter fractional anisotropyMajor risk factorStructural magnetic resonance imagingCross-sectional studyFrontal white matterPrefrontal gray matter volumeMatter structuresMagnetic resonance imagingDiffusion tensor imagingInternal capsuleRisk factorsAnterior limbPrevention strategies
2017
Multimodal Neuroimaging of Frontolimbic Structure and Function Associated With Suicide Attempts in Adolescents and Young Adults With Bipolar Disorder
Johnston JAY, Wang F, Liu J, Blond BN, Wallace A, Liu J, Spencer L, Cox Lippard ET, Purves KL, Landeros-Weisenberger A, Hermes E, Pittman B, Zhang S, King R, Martin A, Oquendo MA, Blumberg HP. Multimodal Neuroimaging of Frontolimbic Structure and Function Associated With Suicide Attempts in Adolescents and Young Adults With Bipolar Disorder. American Journal Of Psychiatry 2017, 174: 667-675. PMID: 28135845, PMCID: PMC5939580, DOI: 10.1176/appi.ajp.2016.15050652.Peer-Reviewed Original ResearchConceptsGray matter volumeBipolar disorderWhite matter integrityFunctional connectivityMatter volumeSuicide attemptsAttempt lethalityPrefrontal connectivitySuicidal ideationYoung adult suicide attemptersAmygdala-prefrontal functional connectivityYoung adultsAmygdala functional connectivitySuicide-related symptomsAdult suicide attemptersPrior suicide attemptsRegional gray matter volumeFrontolimbic structuresNonattempter groupFrontolimbic systemsHigh riskSignificant negative correlationFunctional MROrbitofrontal cortexSuicidal behavior