Toward a Digital Future in Bipolar Disorder Assessment: A Systematic Review of Disruptions in the Rest-Activity Cycle as Measured by Actigraphy
Panchal P, de Queiroz Campos G, Goldman DA, Auerbach RP, Merikangas KR, Swartz HA, Sankar A, Blumberg HP. Toward a Digital Future in Bipolar Disorder Assessment: A Systematic Review of Disruptions in the Rest-Activity Cycle as Measured by Actigraphy. Frontiers In Psychiatry 2022, 13: 780726. PMID: 35677875, PMCID: PMC9167949, DOI: 10.3389/fpsyt.2022.780726.Peer-Reviewed Original ResearchRest-activity patternsBipolar disorderSystematic reviewDepressive episodeActigraphy measuresMore adverse outcomesLonger sleep onset latencyComprehensive systematic reviewDaily activitiesCurrent systematic reviewSleep onset latencyUse of actigraphyRest-activity cycleActivity patternsSpecific phenotypic markersTherapeutic optionsAdverse outcomesEmbase databasesManic symptomsPRISMA guidelinesPrevention optionsOnset latencyPredictive valueCognitive impairmentOverall daily activityIllness Chronology, Brain Morphology and Mixed Symptom Presentations in Older Age Bipolar Disorder: Emerging Findings from the Global Aging & Geriatric Experiments in Bipolar Disorder Database (GAGE –BD) Project
Sajatovic M, Lavin P, Blumberg H, Eyler L. Illness Chronology, Brain Morphology and Mixed Symptom Presentations in Older Age Bipolar Disorder: Emerging Findings from the Global Aging & Geriatric Experiments in Bipolar Disorder Database (GAGE –BD) Project. American Journal Of Geriatric Psychiatry 2022, 30: s8-s9. DOI: 10.1016/j.jagp.2022.01.263.Peer-Reviewed Original ResearchOlder age bipolar disorderBipolar disorderAge-related changesSymptom presentationEvolution of BDLate-onset bipolar disorderBrain structuresMajority of patientsOnset of illnessCourse of illnessGlobal AGEingWorse health outcomesGray matter volumeAge of onsetStructural magnetic resonance imaging (MRI) dataMixed featuresClinical factorsEarly mortalityMixed symptomsWhite matter microstructureClinical correlatesCorrelates of ageDepressive episodeFunctional statusRisk factors