2024
Blood epigenome-wide association studies of suicide attempt in adults with bipolar disorder
Mirza S, Lima C, Del Favero-Campbell A, Rubinstein A, Topolski N, Cabrera-Mendoza B, Kovács E, Blumberg H, Richards J, Williams A, Wemmie J, Magnotta V, Fiedorowicz J, Gaine M, Walss-Bass C, Quevedo J, Soares J, Fries G. Blood epigenome-wide association studies of suicide attempt in adults with bipolar disorder. Translational Psychiatry 2024, 14: 70. PMID: 38296944, PMCID: PMC10831084, DOI: 10.1038/s41398-024-02760-y.Peer-Reviewed Original ResearchConceptsEpigenome-wide association studiesDifferentially methylated regionsDifferentially methylated positionsAssociation studiesCo-methylation network analysisBipolar disorderDNA methylation patternsSuicide attemptsReplication cohortHistory of SAGene ontology analysisSignificant CpG sitesMethylation patternsDNA methylationCpG sitesOntology analysisImmune-related genesEnrichment analysisNon-psychiatric controlsCalcium signalingGenesDNAClinical interviewSA historyNetwork analysis
2012
Integrating Imaging and Genetic Research
Perlis R, Blumberg H. Integrating Imaging and Genetic Research. 2012, 239-252. DOI: 10.1093/med/9780199797608.003.0101.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsBipolar disorderCorticolimbic systemAbstract Neuroimaging studiesHomogeneous patient populationAnterior cingulate cortexPatient populationBrain changesClinical practiceCingulate cortexPersonalized treatmentVentral prefrontalNeuroimaging studiesGenetic association studiesConvergence of findingsMolecular mechanismsAssociation studiesGenetic studiesCommon variationDisordersGenetic researchFuture investigationsImaging