1993
Ischemia as an Excitotoxic Lesion: Protection Against Hippocampal Nerve Cell Loss by Denervation
Diemer N, Johansen F, Benveniste H, Bruhn T, Berg M, Valente E, Jørgensen M. Ischemia as an Excitotoxic Lesion: Protection Against Hippocampal Nerve Cell Loss by Denervation. Acta Neurochirurgica Supplement 1993, 57: 94-101. PMID: 8380675, DOI: 10.1007/978-3-7091-9266-5_14.Peer-Reviewed Original ResearchConceptsPyramidal neuronsIschemic neuron damageVulnerable nerve cellsTransient cerebral ischemiaGABA-ergic interneuronsNerve cell lossMin of ischemiaHippocampal pyramidal neuronsRelease of glutamateExtracellular glutamate releaseKainate/Neuroexcitatory mechanismsNeuron damagePostischemic periodCerebral ischemiaHilus cellsPostischemic hypoperfusionCalcium blockersGlutamate releaseIntact innervationIschemic animalsDenervated ratsDentate hilusReceptor autoradiographyCA1 neurons
1991
Decreased glucose utilization in discrete brain regions of rat in thioacetamide‐induced hepatic encephalopathy as measured with [3H]‐deoxyglucose
Hilgier W, Benveniste H, Diemer N, Albrecht J. Decreased glucose utilization in discrete brain regions of rat in thioacetamide‐induced hepatic encephalopathy as measured with [3H]‐deoxyglucose. Acta Neurologica Scandinavica 1991, 83: 353-355. PMID: 1887755, DOI: 10.1111/j.1600-0404.1991.tb03961.x.Peer-Reviewed Original ResearchConceptsBrain regionsLocal cerebral metabolic rateCerebral metabolic rateDiscrete brain regionsHepatic encephalopathyParticular brain regionsCerebral cortexGlutamatergic neuronsGlutamatergic neurotransmissionMedulla oblongataAuditory cortexGlucose utilizationDeoxyglucose uptakeBioenergetic failureEnergy metabolismRatsCortexPossible linkMetabolic ratePossible contributionThioacetamideOblongataEncephalopathyHippocampusStriatum