Ischemic Damage in Hippocampal CA1 is Dependent on Glutamate Release and Intact Innervation from CA3
Benveniste H, Jørgensen M, Sandberg M, Christensen T, Hagberg H, Diemer N. Ischemic Damage in Hippocampal CA1 is Dependent on Glutamate Release and Intact Innervation from CA3. Cerebrovascular And Brain Metabolism Reviews 1989, 9: 629-639. PMID: 2570785, DOI: 10.1038/jcbfm.1989.90.Peer-Reviewed Original ResearchConceptsCA1 regionPyramidal cellsGlutamate releaseIntact innervationHippocampal tissueCA1 tissueInjection siteIschemia-induced releaseIschemia-induced damageTransient global ischemiaCA1 pyramidal cellsRelease of glutamateGlutamatergic afferentsIschemic damageHippocampal CA1CA1 pyramidsGlobal ischemiaCA3 regionPathogenetic significanceIschemiaNeurotoxic potentialCA3CA1GlutamateInnervation