2005
Neonatal isolation alters the estrous cycle interactions on the acute behavioral effects of cocaine
Kosten T, Sanchez H, Jatlow P, Kehoe P. Neonatal isolation alters the estrous cycle interactions on the acute behavioral effects of cocaine. Psychoneuroendocrinology 2005, 30: 753-761. PMID: 15919581, DOI: 10.1016/j.psyneuen.2005.03.004.Peer-Reviewed Original ResearchConceptsEstrous stageNeonatal isolationBehavioral effectsNH femalesCocaine dosesNon-handled conditionsLow cocaine dosesCocaine plasma levelsEffects of estrogenVentral striatal dopamineAcute behavioral effectsAbility of cocaineHigher cocaine dosesAcquisition of cocaineAcute behavioral responsesMonoamine levelsStriatal dopamineSerotonin levelsPlasma levelsEstrous cyclicityFemale ratsISO ratsIsolation altersDiestrus stageEstrus rats
2004
Neonatal isolation enhances acquisition of cocaine self-administration and food responding in female rats
Kosten T, Sanchez H, Zhang X, Kehoe P. Neonatal isolation enhances acquisition of cocaine self-administration and food responding in female rats. Behavioural Brain Research 2004, 151: 137-149. PMID: 15084429, DOI: 10.1016/j.bbr.2003.08.010.Peer-Reviewed Original ResearchMeSH KeywordsAnalysis of VarianceAnimalsAnimals, NewbornBehavior, AddictiveBody WeightCocaineConditioning, OperantDopamine Uptake InhibitorsDose-Response Relationship, DrugFeeding BehaviorFemaleMaleMotor ActivityRatsRats, Sprague-DawleyReinforcement ScheduleReinforcement, PsychologySelf AdministrationSex FactorsSocial Isolation