2016
The Naturally Occurring Compound Garcinia Indica Selectively Impairs the Reconsolidation of a Cocaine-Associated Memory
Monsey MS, Sanchez H, Taylor JR. The Naturally Occurring Compound Garcinia Indica Selectively Impairs the Reconsolidation of a Cocaine-Associated Memory. Neuropsychopharmacology 2016, 42: 587-597. PMID: 27380937, PMCID: PMC5240167, DOI: 10.1038/npp.2016.117.Peer-Reviewed Original ResearchConceptsCocaine-cue memoriesCocaine self-administration trainingLight/tone cuesCue-induced cocaine-seeking behaviorCocaine-Associated MemorySelf-administration trainingCocaine-seeking behaviorActive lever pressesCue memoryInfusion of cocaineLever extinctionReconsolidation processTone cuesSuch cuesDrug takingMemoryLever pressesCuesReconsolidationNew responsesAbstinenceDrug abuseEnvironmental stimuliCocaine useCocaine access
2010
Reconsolidation of a Cocaine-Associated Stimulus Requires Amygdalar Protein Kinase A
Sanchez H, Quinn JJ, Torregrossa MM, Taylor JR. Reconsolidation of a Cocaine-Associated Stimulus Requires Amygdalar Protein Kinase A. Journal Of Neuroscience 2010, 30: 4401-4407. PMID: 20335476, PMCID: PMC2881637, DOI: 10.1523/jneurosci.3149-09.2010.Peer-Reviewed Original ResearchMeSH KeywordsAmygdalaAnalysis of VarianceAnimalsAssociation LearningCocaineConditioning, OperantCuesCyclic AMPCyclic AMP-Dependent Protein KinasesDopamine Uptake InhibitorsExploratory BehaviorExtinction, PsychologicalMaleProtein Kinase InhibitorsRatsRats, Sprague-DawleyReinforcement, PsychologySelf AdministrationThionucleotidesConceptsSubsequent cue-induced reinstatementCocaine-paired stimulusCue-induced reinstatementLight/tone stimulusIntra-amygdalar infusionLight/toneDrug-paired stimuliNew instrumental responseDrug-associated stimuliIntravenous cocaine infusionsCocaine-induced reinstatementLever extinctionMemory reconsolidationStimulus memoryMemory restabilizationReinstatement testingBehavioral treatmentPKA inhibitor Rp-cAMPSAddictive disordersTone stimuliReconsolidationInstrumental responseCocaine infusionsDrug addictionReinstatement