2001
Defining the specific physiological requirements for c-Myc in T cell development
Douglas N, Jacobs H, Bothwell A, Hayday A. Defining the specific physiological requirements for c-Myc in T cell development. Nature Immunology 2001, 2: 307-315. PMID: 11276201, DOI: 10.1038/86308.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell DifferentiationCell DivisionChimeraFemaleGene Expression Regulation, DevelopmentalGenes, mycGenes, RAG-1MaleMiceMice, Inbred C57BLMice, KnockoutProto-Oncogene Proteins c-mycThymus GlandT-LymphocytesConceptsDevelopmental gene expressionC-MycSpecific physiological requirementsMYC family membersT cell developmentAbstractc-MycN-myc expressionGene expressionDeregulated expressionCell developmentCell growthPhysiological requirementsAge-dependent mannerThymocyte maturationDN stageNormal lymphocytesExpressionNonredundant contributionsDistinct patternsFamily membersCellsLymphomagenesisMaturationLymphocytes
2000
Hex expression suggests a role in the development and function of organs derived from foregut endoderm
Bogue C, Ganea G, Sturm E, Ianucci R, Jacobs H. Hex expression suggests a role in the development and function of organs derived from foregut endoderm. Developmental Dynamics 2000, 219: 84-89. PMID: 10974674, DOI: 10.1002/1097-0177(2000)9999:9999<::aid-dvdy1028>3.0.co;2-5.Peer-Reviewed Original ResearchConceptsExtrahepatic biliary ductsMature animalsMaintenance of functionThymus originatesAdult thyroidDorsal pancreatic budLung expressionBile ductBiliary ductsThymic expressionFunction of organsDuct epitheliumLungThyroidE16.5 embryosLiverEpithelial cellsThymusSeptum transversumMesenchymal cellsPotential roleHex expressionDetectable levelsPharyngeal pouchesOrgans
1998
Fetal Lung mRNA Levels of Hox Genes Are Differentially Altered by Maternal Diabetes and Butyrate in Rats
Jacobs H, Bogue C, Pinter E, Wilson C, Warshaw J, Gross I. Fetal Lung mRNA Levels of Hox Genes Are Differentially Altered by Maternal Diabetes and Butyrate in Rats. Pediatric Research 1998, 44: 99-104. PMID: 9667378, DOI: 10.1203/00006450-199807000-00016.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsButyratesButyric AcidDiabetes Mellitus, ExperimentalEmbryonic and Fetal DevelopmentFemaleGene Expression Regulation, DevelopmentalGenes, HomeoboxGestational AgeHistone Deacetylase InhibitorsLungOrgan Culture TechniquesPregnancyPregnancy in DiabeticsRatsRats, Sprague-DawleyRNA, MessengerTranscription, GeneticConceptsLung developmentLung explantsSurfactant apoproteinExperimental animalsLung mRNA levelsElevated levelsEffect of diabetesFetal rat lung explantsLungs of fetusesRat lung explantsEffect of butyrateAntenatal exposureMaternal diabetesMetabolic abnormalitiesStreptozotocin treatmentLower incidenceNormal ratsDiabetesDexamethasoneLevel of expressionRatsTreatment of explantsSodium butyrateMRNA levelsAlters expression
1996
Expression of Hoxb genes in the developing mouse foregut and lung.
Bogue CW, Lou LJ, Vasavada H, Wilson CM, Jacobs HC. Expression of Hoxb genes in the developing mouse foregut and lung. American Journal Of Respiratory Cell And Molecular Biology 1996, 15: 163-171. PMID: 8703472, DOI: 10.1165/ajrcmb.15.2.8703472.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDigestive SystemEpitheliumFemaleGene Expression Regulation, DevelopmentalGenes, HomeoboxImmunohistochemistryIn Situ HybridizationLungMaleMesodermMiceMice, Inbred StrainsPregnancyRNA Probes