1990
Effect of artificial surfactant on pulmonary function in preterm and full-term lambs
Gladstone I, Ray A, Salafia C, Perez-Fontan J, Mercurio M, Jacobs H. Effect of artificial surfactant on pulmonary function in preterm and full-term lambs. Journal Of Applied Physiology 1990, 69: 465-472. PMID: 2121700, DOI: 10.1152/jappl.1990.69.2.465.Peer-Reviewed Original ResearchConceptsFunctional residual capacityFull-term lambsMean lung volumePreterm lambsLung volumeResidual capacityTest agentsFC-100Higher minimum surface tensionsRespiratory failureLung functionPulmonary functionLung expansionAlveolar washMinimum surface tensionDynamic complianceArtificial surfactantQualitative histologyOxygenationLambsAgentsGas exchangePretermComplianceHistology
1986
Left ventricular performance and contractility before and after volume infusion: a comparative study of preterm and full-term newborn lambs.
Baylen B, Ogata H, Ikegami M, Jacobs H, Jobe A, Emmanouilides G. Left ventricular performance and contractility before and after volume infusion: a comparative study of preterm and full-term newborn lambs. Circulation 1986, 73: 1042-1049. PMID: 3754496, DOI: 10.1161/01.cir.73.5.1042.Peer-Reviewed Original ResearchConceptsFull-term lambsLeft ventricular performanceVolume infusionPreterm lambsVentricular performanceStroke workLeft ventricular peak dP/dtLeft ventricleVentricular peak dP/dtLeft ventricular end-diastolic volumeFull-term newborn lambsVentricular end-diastolic volumeLeft ventricular stroke workPeak dP/dtGreater stroke workPostnatal circulatory adaptationSystemic vascular resistanceVentricular stroke workFull-term animalsDays gestational ageEnd-diastolic volumeLeft ventricular pressureDP/dtVascular resistancePulmonary function
1985
Lung protein leaks in ventilated lambs: effects of gestational age
Jobe A, Jacobs H, Ikegami M, Berry D. Lung protein leaks in ventilated lambs: effects of gestational age. Journal Of Applied Physiology 1985, 58: 1246-1251. PMID: 3988678, DOI: 10.1152/jappl.1985.58.4.1246.Peer-Reviewed Original ResearchConceptsDays gestational ageGestational ageFull-term lambsGroups of lambsVentilated lambsLung tissueAlveolar washBlood gas valuesNatural sheep surfactantPremature lambsPreterm lambsPremature lungIntravascular injectionSheep surfactantLung proteinGas valuesPCO2 valuesAgeAlveoliAirwayLambsBidirectional fluxesTissueGroupAlbumin