2015
Role of Chitinase 3–like-1 and Semaphorin 7a in Pulmonary Melanoma Metastasis
Ma B, Herzog EL, Lee CG, Peng X, Lee CM, Chen X, Rockwell S, Koo JS, Kluger H, Herbst RS, Sznol M, Elias JA. Role of Chitinase 3–like-1 and Semaphorin 7a in Pulmonary Melanoma Metastasis. Cancer Research 2015, 75: 487-496. PMID: 25511377, PMCID: PMC4321965, DOI: 10.1158/0008-5472.can-13-3339.Peer-Reviewed Original ResearchConceptsMelanoma lung metastasisPulmonary melanoma metastasesPulmonary metastasesLung metastasesMelanoma metastasesGenetic deletionBreast cancer cellsPlexin C1 receptorsPulmonary microenvironmentPoor prognosisSemaphorin 7AMelanoma spreadChitinase 3MetastasisCHI3L1Cancer progressionSema7AInhibitory wayCancer cellsReceptorsSignificant reductionΒ1 integrinNovel pathwayCritical roleIL13Rα2
2009
Regulation of non-AU-rich element containing c-fms proto-oncogene expression by HuR in breast cancer
Woo HH, Zhou Y, Yi X, David CL, Zheng W, Gilmore-Hebert M, Kluger HM, Ulukus EC, Baker T, Stoffer JB, Chambers SK. Regulation of non-AU-rich element containing c-fms proto-oncogene expression by HuR in breast cancer. Oncogene 2009, 28: 1176-1186. PMID: 19151756, DOI: 10.1038/onc.2008.469.Peer-Reviewed Original ResearchConceptsBreast cancerBreast cancer tissue arrayNuclear HuR expressionBreast cancer progressionC-fmsC-fms proto-oncogene expressionNodal metastasisPoor prognosisPoor survivalProto-oncogene c-fmsProto-oncogene expressionBreast tumorsGlucocorticoid stimulationTissue arraysCancer progressionHuR expressionRNA expressionDirect targetC-fms mRNACancer biologyC-fms RNACancer