2022
Inert Pepper aptamer-mediated endogenous mRNA recognition and imaging in living cells.
Wang Q, Xiao F, Su H, Liu H, Xu J, Tang H, Qin S, Fang Z, Lu Z, Wu J, Weng X, Zhou X. Inert Pepper aptamer-mediated endogenous mRNA recognition and imaging in living cells. Nucleic Acids Res 2022, 50: e84. PMID: 35580055, DOI: 10.1093/nar/gkac368.Peer-Reviewed Original ResearchMapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID
Na Z, Dai X, Zheng SJ, Bryant CJ, Loh KH, Su H, Luo Y, Buhagiar AF, Cao X, Baserga SJ, Chen S, Slavoff SA. Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID. Molecular Cell 2022, 82: 2900-2911.e7. PMID: 35905735, PMCID: PMC9662605, DOI: 10.1016/j.molcel.2022.06.035.Peer-Reviewed Original ResearchConceptsSubcellular localizationProximity biotinylationSmall open reading framesAlternative proteinsOpen reading frameHigh-throughput technologiesSubnuclear organellesCanonical proteinsRRNA transcriptionSubcellular compartmentsReading frameProteogenomic identificationProtein compositionAmino acidsMicroproteinsProteinBiotinylationLocalizationTurboIDTranscriptionOrganellesMouse modelPolypeptideNucleoliExpression
2021
Photoactive G-Quadruplex Ligand Identifies Multiple G-Quadruplex-Related Proteins with Extensive Sequence Tolerance in the Cellular Environment.
Su H, Xu J, Chen Y, Wang Q, Lu Z, Chen Y, Chen K, Han S, Fang Z, Wang P, Yuan BF, Zhou X. Photoactive G-Quadruplex Ligand Identifies Multiple G-Quadruplex-Related Proteins with Extensive Sequence Tolerance in the Cellular Environment. J Am Chem Soc 2021, 143: 1917-1923. PMID: 33471508, DOI: 10.1021/jacs.0c10792.Peer-Reviewed Original Research
2019
High-efficiency and integrable DNA arithmetic and logic system based on strand displacement synthesis.
Su H, Xu J, Wang Q, Wang F, Zhou X. High-efficiency and integrable DNA arithmetic and logic system based on strand displacement synthesis. Nat Commun 2019, 10: 5390. PMID: 31772166, DOI: 10.1038/s41467-019-13310-2.Peer-Reviewed Original Research
2018
Precise Antibody-Independent m6A Identification via 4SedTTP-Involved and FTO-Assisted Strategy at Single-Nucleotide Resolution.
Hong T, Yuan Y, Chen Z, Xi K, Wang T, Xie Y, He Z, Su H, Zhou Y, Tan ZJ, Weng X, Zhou X. Precise Antibody-Independent m6A Identification via 4SedTTP-Involved and FTO-Assisted Strategy at Single-Nucleotide Resolution. J Am Chem Soc 2018, 140: 5886-5889. PMID: 29489347, DOI: 10.1021/jacs.7b13633.Peer-Reviewed Original Research
2017
Quantitative and Comparative Profiling of Protease Substrates through a Genetically Encoded Multifunctional Photocrosslinker.
He D, Xie X, Yang F, Zhang H, Su H, Ge Y, Song H, Chen PR. Quantitative and Comparative Profiling of Protease Substrates through a Genetically Encoded Multifunctional Photocrosslinker. Angew Chem Int Ed Engl 2017, 56: 14521-14525. PMID: 28940571, DOI: 10.1002/anie.201708151.Peer-Reviewed Original Research
2016
Obtaining More Accurate Signals: Spatiotemporal Imaging of Cancer Sites Enabled by a Photoactivatable Aptamer-Based Strategy.
Xiao H, Chen Y, Yuan E, Li W, Jiang Z, Wei L, Su H, Zeng W, Gan Y, Wang Z, Yuan B, Qin S, Leng X, Zhou X, Liu S, Zhou X. Obtaining More Accurate Signals: Spatiotemporal Imaging of Cancer Sites Enabled by a Photoactivatable Aptamer-Based Strategy. ACS Appl Mater Interfaces 2016, 8: 23542-8. PMID: 27550088, DOI: 10.1021/acsami.6b07450.Peer-Reviewed Original ResearchHighly Selective Detection of 5-Methylcytosine in Genomic DNA Based on Asymmetric PCR and Specific DNA Damaging Reagents.
Wang Y, Liu C, Wang T, Hong T, Su H, Yu S, Song H, Liu S, Zhou X, Mao W, Zhou X. Highly Selective Detection of 5-Methylcytosine in Genomic DNA Based on Asymmetric PCR and Specific DNA Damaging Reagents. Anal Chem 2016, 88: 3348-53. PMID: 26859062, DOI: 10.1021/acs.analchem.5b04939.Peer-Reviewed Original Research
2015
Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein.
Wang T, Hong T, Huang Y, Su H, Wu F, Chen Y, Wei L, Huang W, Hua X, Xia Y, Xu J, Gan J, Yuan B, Feng Y, Zhang X, Yang CG, Zhou X. Fluorescein Derivatives as Bifunctional Molecules for the Simultaneous Inhibiting and Labeling of FTO Protein. J Am Chem Soc 2015, 137: 13736-9. PMID: 26457839, DOI: 10.1021/jacs.5b06690.Peer-Reviewed Original Research