Nucleation by rRNA Dictates the Precision of Nucleolus Assembly
Falahati H, Pelham-Webb B, Blythe S, Wieschaus E. Nucleation by rRNA Dictates the Precision of Nucleolus Assembly. Current Biology 2016, 26: 277-285. PMID: 26776729, PMCID: PMC5866055, DOI: 10.1016/j.cub.2015.11.065.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell NucleolusDNA, RibosomalDrosophila melanogasterEmbryo, NonmammalianNuclear ProteinsRNA, RibosomalTranscription, GeneticConceptsMembrane-less organellesTranscription of rRNANucleolar proteinsCellular functionsNucleolus formationInitial assemblyD. melanogaster embryosDifferent cellular functionsSpecific cellular functionsWild-type embryosRole of rRNARibosomal biogenesisNucleolus assemblySuch organellesNucleoplasmic concentrationIntracellular compartmentsRRNAOrganellesSpatiotemporal precisionTranscriptionNucleoliEmbryosProteinAssemblyBiological systems