2013
Early-Onset Alopecia and Amyotrophic Lateral Sclerosis: A Cohort Study
Fondell E, Fitzgerald KC, Falcone GJ, O'Reilly É, Ascherio A. Early-Onset Alopecia and Amyotrophic Lateral Sclerosis: A Cohort Study. American Journal Of Epidemiology 2013, 178: 1146-1149. PMID: 23942216, PMCID: PMC3783095, DOI: 10.1093/aje/kwt096.Peer-Reviewed Original ResearchConceptsAge 45 yearsEarly-onset alopeciaRisk of ALSExtensive alopeciaTAR DNA-binding protein 43DNA-binding protein 43Health Professionals FollowAmyotrophic lateral sclerosisEarly baldingProfessionals FollowCohort studyModerate alopeciaProtein 43Large cohortHigh riskLateral sclerosisUS menAlopeciaSingle nucleotide polymorphism (SNP) variantsPolymorphism variantsALSMenFurther investigationRiskBalding
2012
Premorbid body mass index and risk of amyotrophic lateral sclerosis
O'Reilly ÉJ, Wang H, Weisskopf MG, Fitzgerald KC, Falcone G, McCullough ML, Thun M, Park Y, Kolonel LN, Ascherio A. Premorbid body mass index and risk of amyotrophic lateral sclerosis. Amyotrophic Lateral Sclerosis And Frontotemporal Degeneration 2012, 14: 205-211. PMID: 23134505, PMCID: PMC3615420, DOI: 10.3109/21678421.2012.735240.Peer-Reviewed Original ResearchConceptsBody mass indexHealthy body mass indexPremorbid body mass indexALS ratesMass indexCohort-specific Cox proportional hazard modelsLower premorbid Body Mass IndexLower body mass indexCox proportional hazards modelAmyotrophic lateral sclerosis riskProportional hazards modelAmyotrophic lateral sclerosisRandom-effects modelOngoing cohortUnhealthy weightLateral sclerosisHazards modelUndiagnosed diseaseCurrent weightWeight lossObeseALSAssociationMalesFemales