2022
The association between beta‐blockers and outcomes in patients with heart failure and concurrent Alzheimer's disease and related dementias
Gilstrap L, Cohen A, Ouellet GM, Goyal P, Gladders B, Flint D, Skinner J. The association between beta‐blockers and outcomes in patients with heart failure and concurrent Alzheimer's disease and related dementias. Journal Of The American Geriatrics Society 2022, 71: 404-413. PMID: 36240493, DOI: 10.1111/jgs.18086.Peer-Reviewed Original ResearchMeSH KeywordsAdrenergic beta-AntagonistsAgedAlzheimer DiseaseHeart FailureHospitalizationHumansMedicareStroke VolumeUnited StatesConceptsHigh riskBB useHeart failureAlzheimer's diseaseLong-term mortality ratesConcurrent Alzheimer's diseaseBeta-blocker useReduced ejection fractionMedicare Part ARisk/benefitBB therapyEjection fractionContemporary patientsHFrEFHigh prevalenceSimilar riskMortality ratePatientsCognitive impairmentMortalityDiseaseADRDRiskTherapyOutcomes
2012
Effect of Cardiac Resynchronization Therapy on the Risk of First and Recurrent Ventricular Tachyarrhythmic Events in MADIT-CRT
Ouellet G, Huang DT, Moss AJ, Hall WJ, Barsheshet A, McNitt S, Klein H, Zareba W, Goldenberg I. Effect of Cardiac Resynchronization Therapy on the Risk of First and Recurrent Ventricular Tachyarrhythmic Events in MADIT-CRT. Journal Of The American College Of Cardiology 2012, 60: 1809-1816. PMID: 23040580, DOI: 10.1016/j.jacc.2012.05.057.Peer-Reviewed Original ResearchConceptsLeft bundle branch blockVentricular tachyarrhythmic eventsNon-LBBB patientsFirst arrhythmic eventCardiac resynchronization therapyMADIT-CRTResynchronization therapyArrhythmic riskTachyarrhythmic eventsArrhythmic eventsSubsequent heart failureCRT-D therapyBundle branch blockCox proportional hazardsRisk of FirstHeart failureActive treatmentEfficacy analysisBranch blockPatientsProportional hazardsMultivariate analysisTherapyRegression modelingRiskEffectiveness of Cardiac Resynchronization Therapy in Diabetic Patients with Ischemic and Nonischemic Cardiomyopathy
George J, Barsheshet A, Moss AJ, Martin D, Ouellet G, McNitt S, Goldenberg I. Effectiveness of Cardiac Resynchronization Therapy in Diabetic Patients with Ischemic and Nonischemic Cardiomyopathy. Annals Of Noninvasive Electrocardiology 2012, 17: 14-21. PMID: 22276624, PMCID: PMC6932461, DOI: 10.1111/j.1542-474x.2011.00476.x.Peer-Reviewed Original ResearchConceptsNonischemic cardiomyopathyDiabetes mellitusProportional hazards regression modelingCardiac resynchronization therapyMADIT-CRTClinical responseEchocardiographic responseNonischemic patientsDiabetic patientsDM patientsResynchronization therapyClinical benefitCardiomyopathyPatientsRegression modelingCRTMellitusResponseTherapyDefibrillator