Meta-Analysis of Molecular Imaging of Serotonin Transporters in Major Depression
Gryglewski G, Lanzenberger R, Kranz GS, Cumming P. Meta-Analysis of Molecular Imaging of Serotonin Transporters in Major Depression. Cerebrovascular And Brain Metabolism Reviews 2014, 34: 1096-1103. PMID: 24802331, PMCID: PMC4083395, DOI: 10.1038/jcbfm.2014.82.Peer-Reviewed Original ResearchConceptsMajor depressive disorderSerotonin selective reuptake inhibitorsBrains of patientsSeverity of depressionMolecular imaging findingsPositron emission tomographySerotonin reuptake sitesSingle photon emissionMore severe reductionsSignificant comorbiditiesReuptake inhibitorsImaging findingsMDD patientsControl subjectsMonoamine theoryReuptake sitesDepressive disorderSerotonergic neurotransmissionMajor depressionMolecular imaging studiesStudy populationCingulate cortexMeta-AnalysisEmission tomographyImaging studies