Serotonergic modulation of effective connectivity in an associative relearning network during task and rest
Reed MB, Klöbl M, Godbersen GM, Handschuh PA, Ritter V, Spurny-Dworak B, Unterholzner J, Kraus C, Gryglewski G, Winkler D, Seiger R, Vanicek T, Hahn A, Lanzenberger R. Serotonergic modulation of effective connectivity in an associative relearning network during task and rest. NeuroImage 2022, 249: 118887. PMID: 34999203, DOI: 10.1016/j.neuroimage.2022.118887.Peer-Reviewed Original ResearchConceptsRight angular gyrusAnterior cingulate cortexEffective connectivityRight insulaCognitive flexibilityAngular gyrusCingulate cortexAssociative learning taskAssociative learningLearning taskTask connectivityLearning phaseInsulaGray matter volume changesSelective serotonin reuptake inhibitor escitalopramDouble-blind designNeuroplastic changesGyrusTaskParticipantsSSRI intakeCortexEffective connectionSerotonergic modulationConnectivity