2020
Concurrent use of rabacfosadine and L‐asparaginase for relapsed or refractory multicentric lymphoma in dogs
Cawley J, Wright Z, Meleo K, Post G, Clifford C, Vickery K, Vail D, Bergman P, Thamm D. Concurrent use of rabacfosadine and L‐asparaginase for relapsed or refractory multicentric lymphoma in dogs. Journal Of Veterinary Internal Medicine 2020, 34: 882-889. PMID: 32064697, PMCID: PMC7096650, DOI: 10.1111/jvim.15723.Peer-Reviewed Original ResearchConceptsMedian progression-free survival timeOverall response rateComplete responseMulticentric lymphomaAdverse eventsL-asparaginaseProspective single-arm clinical trialProgression-free survival timeSingle-arm clinical trialNegative prognostic factorRelapse of lymphomaTreatment of lymphomaNovel antineoplastic agentPrognostic factorsChemotherapy protocolsClinical trialsRabacfosadineSurvival timeIU/Response rateClinical importanceLymphomaMultivariate analysisAntineoplastic agentsConcurrent use
2012
Feline exocrine pancreatic carcinoma: a retrospective study of 34 cases
Linderman M, Brodsky E, de Lorimier L, Clifford C, Post G. Feline exocrine pancreatic carcinoma: a retrospective study of 34 cases. Veterinary And Comparative Oncology 2012, 11: 208-218. PMID: 22612638, DOI: 10.1111/j.1476-5829.2012.00320.x.Peer-Reviewed Original ResearchConceptsMedian survivalRetrospective studySurvival timeNon-steroidal anti-inflammatory drug therapyAnti-inflammatory drug therapyOverall median survivalPalpable abdominal massTime of diagnosisMedian survival timeExocrine pancreatic carcinomaHigh metastatic rateMetastatic diseaseAbdominal massClinical presentationMetastatic ratePoor prognosisPrognostic indicatorAggressive tumorsDrug therapyAbdominal effusionPancreatic cancerClinical signsPancreatic carcinomaPatientsWeight loss
2011
Single‐agent gemcitabine chemotherapy in dogs with hepatocellular carcinomas
Elpiner A, Brodsky E, Hazzah T, Post G. Single‐agent gemcitabine chemotherapy in dogs with hepatocellular carcinomas. Veterinary And Comparative Oncology 2011, 9: 260-268. PMID: 22077406, DOI: 10.1111/j.1476-5829.2011.00262.x.Peer-Reviewed Original ResearchConceptsHepatocellular carcinomaGemcitabine chemotherapyMedian progression-free intervalSingle-agent gemcitabine chemotherapyGrade III neutropeniaNonresectable hepatocellular carcinomaSerial abdominal ultrasoundsTolerability of gemcitabineProgression-free intervalMedian survival timeAbdominal ultrasoundIncomplete resectionFree intervalSurvival timeDogsBest treatmentChemotherapyGemcitabineCarcinomaToxicityDaysVomitingNeutropeniaTolerabilityResection
2009
Evaluation of a multidrug chemotherapy protocol with mitoxantrone based maintenance (CHOP‐MA) for the treatment of canine lymphoma
Daters A, Mauldin G, Mauldin G, Brodsky E, Post G. Evaluation of a multidrug chemotherapy protocol with mitoxantrone based maintenance (CHOP‐MA) for the treatment of canine lymphoma. Veterinary And Comparative Oncology 2009, 8: 11-22. PMID: 20230577, DOI: 10.1111/j.1476-5829.2009.00199.x.Peer-Reviewed Original ResearchConceptsMultidrug chemotherapy protocolMulticentric lymphomaMedian survivalChemotherapy protocolsSurvival timeOverall median survivalDose of doxorubicinCanine multicentric lymphomaMitoxantrone dosesOverall remissionSteroid administrationMedian remissionHistorical controlsRemission timeCanine lymphomaLymphomaRemissionMitoxantroneDogsFurther studiesL-asparaginaseSurvivalDoxorubicinDaysHypercalcaemiaAsparaginase and MOPP Treatment of Dogs with Lymphoma
Brodsky E, Maudlin G, Lachowicz J, Post G. Asparaginase and MOPP Treatment of Dogs with Lymphoma. Journal Of Veterinary Internal Medicine 2009, 23: 578-584. PMID: 19645842, DOI: 10.1111/j.1939-1676.2009.0289.x.Peer-Reviewed Original ResearchConceptsOverall survival timeT-cell lymphomaT-cell phenotypeEntire study populationStudy populationSurvival timeMulticentric T-cell lymphomaMedian overall survival timeProgression-free survival timePresence of hypercalcemiaOverall response rateReferral veterinary hospitalAntigen receptor rearrangementMedian PFSMOPP chemotherapyMOPP treatmentPrevious chemotherapyLonger PFSChemotherapy protocolsMulticentric lymphomaRetrospective studyPolymerase chain reactionCytologic diagnosisReceptor rearrangementLymphoma