A Phase I Clinical Trial Evaluating Imatinib Mesylate (Gleevec) in Tumor‐Bearing Cats
Lachowicz J, Post G, Brodsky E. A Phase I Clinical Trial Evaluating Imatinib Mesylate (Gleevec) in Tumor‐Bearing Cats. Journal Of Veterinary Internal Medicine 2005, 19: 860-864. PMID: 16355681, DOI: 10.1111/j.1939-1676.2005.tb02778.x.Peer-Reviewed Original ResearchConceptsPhase I clinical trialPO q24hImatinib mesylateClinical trialsSerum biochemistryMinimal gastrointestinal toxicityTumor-bearing catsTumor‐Bearing CatsDiagnosis of fibrosarcomaSquamous cell carcinomaTyrosine kinase inhibitorsMast cell tumorsSigns of toxicityAbdominal ultrasonographyConcurrent chemotherapyGastrointestinal toxicityDose escalationCell carcinomaCell tumorsThoracic radiographsQ24hRadiation therapyMost catsFurther evaluationKinase inhibitors