2017
Alternating Rabacfosadine/Doxorubicin: Efficacy and Tolerability in Naïve Canine Multicentric Lymphoma
Thamm D, Vail D, Post G, Fan T, Phillips B, Axiak‐Bechtel S, Elmslie R, Klein M, Ruslander D. Alternating Rabacfosadine/Doxorubicin: Efficacy and Tolerability in Naïve Canine Multicentric Lymphoma. Journal Of Veterinary Internal Medicine 2017, 31: 872-878. PMID: 28370378, PMCID: PMC5435064, DOI: 10.1111/jvim.14700.Peer-Reviewed Original ResearchConceptsProgression-free intervalMulticentric lymphomaComplete responseOverall median progression-free intervalMedian progression-free intervalMulticenter prospective clinical trialSubstantial single-agent activityAdverse effect profileAssessment of remissionMost adverse eventsProspective clinical trialsSingle-agent activityLong-term outcomesOverall response rateCanine multicentric lymphomaDermatologic AEsHematologic AEsClinicopathological evaluationAdverse eventsChemotherapy combinationsCombination chemotherapyTreatment visitsUntreated lymphomaEffect profilePulmonary fibrosis
2009
Evaluation of a multidrug chemotherapy protocol with mitoxantrone based maintenance (CHOP‐MA) for the treatment of canine lymphoma
Daters A, Mauldin G, Mauldin G, Brodsky E, Post G. Evaluation of a multidrug chemotherapy protocol with mitoxantrone based maintenance (CHOP‐MA) for the treatment of canine lymphoma. Veterinary And Comparative Oncology 2009, 8: 11-22. PMID: 20230577, DOI: 10.1111/j.1476-5829.2009.00199.x.Peer-Reviewed Original ResearchConceptsMultidrug chemotherapy protocolMulticentric lymphomaMedian survivalChemotherapy protocolsSurvival timeOverall median survivalDose of doxorubicinCanine multicentric lymphomaMitoxantrone dosesOverall remissionSteroid administrationMedian remissionHistorical controlsRemission timeCanine lymphomaLymphomaRemissionMitoxantroneDogsFurther studiesL-asparaginaseSurvivalDoxorubicinDaysHypercalcaemia