Histone demethylase KDM5B is critical for PI3K‐AKT‐mTOR signaling and stemness of melanoma
Yan Q, Zhang S, Meeth K, Micevic G, Bosenberg M. Histone demethylase KDM5B is critical for PI3K‐AKT‐mTOR signaling and stemness of melanoma. The FASEB Journal 2017, 31 DOI: 10.1096/fasebj.31.1_supplement.468.1.Peer-Reviewed Original ResearchKnockdown of KDM5BHistone demethylase KDM5BMTOR signalingPI3K-AktImmune checkpoint blockadeEpigenetic stateMouse melanoma cellsCancer stem cellsMouse melanoma modelMPC populationKDM5BMelanoma formationCheckpoint blockadeTumor initiationStem cellsMelanoma modelMelanoma cellsCareer Development AwardKnockdownSignalingPilot grantsMelanoma