2002
Computed Tomography (CT)
Burns A, Pearlson G. Computed Tomography (CT). 2002, 351-354. DOI: 10.1002/0470846410.ch63.Peer-Reviewed Original ResearchComputed tomographyCT scanLate-onset schizophreniaNormal pressure hydrocephalusPresence of dementiaTypes of dementiaSequential CT scansOld age psychiatryComputed tomography scanningSingle photon emissionCT scan analysisCerebral atrophyCerebral changesCortical atrophyPressure hydrocephalusIntracranial haematomaVascular lesionsDementia syndromesDifferential diagnosisOnset schizophreniaIndividual patientsTreatment resistanceTemporal lobeNon-invasive techniqueAlzheimer's disease
1996
CT measurement of suprasellar cistern predicts rate of cognitive decline in Alzheimer's disease
Aylward E, Rasmusson D, Brandt J, Raimundo L, Folstein M, Pearlson G. CT measurement of suprasellar cistern predicts rate of cognitive decline in Alzheimer's disease. Journal Of The International Neuropsychological Society 1996, 2: 89-95. PMID: 9375193, DOI: 10.1017/s135561770000093x.Peer-Reviewed Original ResearchConceptsSuprasellar cisternAlzheimer's diseaseAD patientsCT measuresQuantitative computed tomography (CT) measuresMini-Mental State Exam scoreCT measurementsComputed tomography measuresProbable Alzheimer's diseaseState Exam scoreBicaudate ratioBifrontal ratioNeurocognitive declineLateral ventricleThird ventricleCT scanTomography measuresCognitive declineCognitive functionPatientsAdaptive functioningDiseaseScansNeuropsychological measuresCognitive functioning
1991
Centrum semiovale white matter CT changes associated with normal ageing, Alzheimer's disease and late life depression with and without reversible dementia
Pearlson G, Rabins P, Burns A. Centrum semiovale white matter CT changes associated with normal ageing, Alzheimer's disease and late life depression with and without reversible dementia. Psychological Medicine 1991, 21: 321-328. PMID: 1876637, DOI: 10.1017/s0033291700020420.Peer-Reviewed Original ResearchConceptsAlzheimer's diseaseCT attenuation numbersGray matterAttenuation numberCranial CT scanLate-life depressionElderly patientsReversible dementiaPatient groupCT changesLife depressionMajor depressionCentrum semiovaleAttenuation valuesCT scanNormal controlsElderly controlsNeuropsychological evaluationNormal agingDiseasePatientsDepressionCognitive tasksDementiaReliable means
1989
Structural brain CT changes and cognitive deficits in elderly depressives with and without reversible dementia (‘pseudodementia’)*
Pearlson G, Rabins P, Kim W, Speedie L, Moberg P, Burns A, Bascom M. Structural brain CT changes and cognitive deficits in elderly depressives with and without reversible dementia (‘pseudodementia’)*. Psychological Medicine 1989, 19: 573-584. PMID: 2798631, DOI: 10.1017/s003329170002417x.Peer-Reviewed Original ResearchConceptsMini-Mental State ExaminationVentricular brain ratioAD patientsDepressed patientsNormal controlsDSM-III major depressionCognitive deficitsShort-term progressionStructural brain abnormalitiesCranial CT scanProbable Alzheimer's diseaseCT attenuation valuesCT valuesReversible dementiaElderly patientsMost patientsBrain ratioCT attenuation numbersCT changesElderly depressivesBrain abnormalitiesDementia syndromesMajor depressionCT scanPatients
1986
STRUCTURAL BRAIN CORRELATES OF EMOTIONAL DISORDER IN MULTIPLE SCLEROSIS
RABINS P, BROOKS B, O'DONNELL P, PEARLSON G, MOBERG P, JUBELT B, COYLE P, DALOS N, FOLSTEIN M. STRUCTURAL BRAIN CORRELATES OF EMOTIONAL DISORDER IN MULTIPLE SCLEROSIS. Brain 1986, 109: 585-597. PMID: 3730806, DOI: 10.1093/brain/109.4.585.Peer-Reviewed Original ResearchConceptsStable spinal cord injuriesMini-Mental State ExaminationMultiple sclerosisBrain involvementSCI patientsMS patientsDepression scoresMean General Health Questionnaire scoresProgressive multiple sclerosisDefinite multiple sclerosisGeneral Health Questionnaire scoresSpinal cord injuryMean depression scoreStructural brain correlatesCord lesionsFunctional disabilityCord injuryNeurological impairmentCT scanQuestionnaire scoresPatientsState ExaminationCognitive disordersAbnormal rangeOne-year studyCerebral ventricular size and cerebrospinal fluid acetylcholinesterase levels in senile dementia of the Alzheimer type
Pearlson G, Tune L. Cerebral ventricular size and cerebrospinal fluid acetylcholinesterase levels in senile dementia of the Alzheimer type. Psychiatry Research 1986, 17: 23-29. PMID: 3484831, DOI: 10.1016/0165-1781(86)90038-7.Peer-Reviewed Original ResearchConceptsVentricle-brain ratioMini-Mental State ExaminationSenile dementiaComputed tomographyAlzheimer typeCerebrospinal fluid acetylcholinesterase activityLateral ventricle-brain ratiosCerebral ventricular sizeDuration of illnessAChE activityCSF AChE activityDegree of dementiaCerebral atrophyVentricular sizeCT scanDilutional effectState ExaminationCognitive impairmentAcetylcholinesterase levelsRadioenzymatic assayDementiaAcetylcholinesterase activityLaboratory dataPatientsSignificant correlation
1983
Mood Change following Bilateral Hemisphere Brain Injury
Lipsey J, Robinson R, Pearlson G, Rao K, Price T. Mood Change following Bilateral Hemisphere Brain Injury. The British Journal Of Psychiatry 1983, 143: 266-273. PMID: 6626839, DOI: 10.1192/bjp.143.3.266.Peer-Reviewed Original ResearchConceptsHemisphere brain injuryFunctional physical impairmentBrain injuryCognitive impairmentPhysical impairmentLeft frontal lobe lesionFrontal lobe lesionsThromboembolic strokeBrain lesionsSuch injuriesCT scanLesion locationDepression severityLobe lesionsLesion proximityDepressive symptomatologyLesion ageFrontal poleInjuryMood changesPatientsImpairmentMood ScaleLesionsDepression
1982
Use of CT scanning in psychiatry
Pearlson G, Veroff A, Wise T. Use of CT scanning in psychiatry. Journal Of The Academy Of Consultation-Liaison Psychiatry 1982, 23: 993-1004. PMID: 7178411, DOI: 10.1016/s0033-3182(82)73291-8.Peer-Reviewed Original ResearchCT scan and neuropsychological correlates of Alzheimer's Disease and Huntington's Disease
Veroff A, Pearlson G, Ahn H. CT scan and neuropsychological correlates of Alzheimer's Disease and Huntington's Disease. Brain And Cognition 1982, 1: 177-184. PMID: 6242676, DOI: 10.1016/0278-2626(82)90015-x.Peer-Reviewed Original ResearchConceptsDisease patientsAlzheimer's diseaseAlzheimer's disease patientsCT scan interpretationHuntington's disease patientsCT scan informationCT attenuation valuesClinical characteristicsPrimary neuropathologyDementia syndromesCT scanScan interpretationNormal agingDiseaseHuntington's diseaseAphasia subtypesNeuropsychological correlatesPatientsSignificant correlationDouble dissociationAttenuation valuesRecent studiesScan informationLobe densityNeuropathology