2013
Transmission of Tuberculosis in Resource-Limited Settings
Kompala T, Shenoi SV, Friedland G. Transmission of Tuberculosis in Resource-Limited Settings. Current HIV/AIDS Reports 2013, 10: 264-272. PMID: 23824469, PMCID: PMC3809054, DOI: 10.1007/s11904-013-0164-x.Peer-Reviewed Original ResearchConceptsDrug-resistant TBTB transmissionCommunity settingsInfection controlHigh HIV prevalenceInfection control practicesTransmission of tuberculosisHousehold contact tracingResource limited settingsHealth care facilitiesResource-constrained settingsHIV prevalenceTB epidemicContinued transmissionCommon siteUnrecognized transmissionContact tracingCommunity sitesControl practicesHold promiseRecent studiesTransmission reductionIntensive caseSettingTB
2012
Nosocomial Transmission of Extensively Drug-Resistant Tuberculosis in a Rural Hospital in South Africa
Gandhi NR, Weissman D, Moodley P, Ramathal M, Elson I, Kreiswirth BN, Mathema B, Shashkina E, Rothenberg R, Moll AP, Friedland G, Sturm AW, Shah NS. Nosocomial Transmission of Extensively Drug-Resistant Tuberculosis in a Rural Hospital in South Africa. The Journal Of Infectious Diseases 2012, 207: 9-17. PMID: 23166374, PMCID: PMC3523793, DOI: 10.1093/infdis/jis631.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntitubercular AgentsCluster AnalysisCross InfectionDrug Therapy, CombinationEthambutolExtensively Drug-Resistant TuberculosisFemaleGenotypeHIV InfectionsHospitals, RuralHumansIsoniazidMaleMutationMycobacterium tuberculosisPolymorphism, Restriction Fragment LengthPrevalencePyrazinamideRetrospective StudiesRifampinSequence Analysis, DNASouth AfricaConceptsDrug-resistant tuberculosisHuman immunodeficiency virusNosocomial transmissionEpidemiologic linkExtensively Drug-Resistant TuberculosisPoor infection controlSmear-positive tuberculosisMultidrug-resistant tuberculosisHigh HIV prevalencePoint-source outbreakGlobal public health threatPublic health threatResistance-determining regionXDR tuberculosisImmunodeficiency virusHIV prevalenceObservational studyInfection controlRural hospitalsPatientsTuberculosisTugela FerryFragment length polymorphism analysisHealth threatRestriction fragment length polymorphism analysisTuberculosis infection control in a high drug-resistance setting in rural South Africa: Information, motivation, and behavioral skills
Kanjee Z, Amico KR, Li F, Mbolekwa K, Moll AP, Friedland GH. Tuberculosis infection control in a high drug-resistance setting in rural South Africa: Information, motivation, and behavioral skills. Journal Of Infection And Public Health 2012, 5: 67-81. PMID: 22341846, DOI: 10.1016/j.jiph.2011.10.008.Peer-Reviewed Original ResearchConceptsTB infection controlRural South African hospitalSouth African hospitalsInfection controlHIV statusAfrican hospitalsTuberculosis infection controlDrug-resistant tuberculosisBehavioral skillsCough hygieneSocial support itemsPresent studyRural South AfricaResource-limited facilitiesHigh-risk areasAnonymous questionnaireIMB modelTuberculosisRespondents' knowledgeSuch interventionsHospitalHCWsIC practicesMost respondentsSocial support
2011
Tuberculosis infection control in rural South Africa: survey of knowledge, attitude and practice in hospital staff
Kanjee Z, Catterick K, Moll AP, Amico KR, Friedland GH. Tuberculosis infection control in rural South Africa: survey of knowledge, attitude and practice in hospital staff. Journal Of Hospital Infection 2011, 79: 333-338. PMID: 21978608, DOI: 10.1016/j.jhin.2011.06.017.Peer-Reviewed Original ResearchConceptsMDR-TB/XDRHuman immunodeficiency virus statusRural South African hospitalNosocomial TB transmissionStigma of TBTuberculosis infection controlTB/HIVDrug-resistant TBInfection control knowledgeHealth informationSouth African hospitalsSurvey of knowledgeBehavioral change interventionsTB-ICTB infectionXDR-TBTB deathsTB transmissionVirus statusHealthcare workersAfrican hospitalsInfection controlHospital staffRural South AfricaBaseline assessmentPrevalence of methicillin-resistant Staphylococcus aureus nasal carriage among hospitalised patients with tuberculosis in rural KwaZulu-Natal
Heysell SK, Shenoi SV, Catterick K, Thomas TA, Friedland G. Prevalence of methicillin-resistant Staphylococcus aureus nasal carriage among hospitalised patients with tuberculosis in rural KwaZulu-Natal. South African Medical Journal 2011, 101: 332-334. PMID: 21837877, PMCID: PMC3628595, DOI: 10.7196/samj.4462.Peer-Reviewed Original ResearchConceptsMethicillin-resistant Staphylococcus aureusTB wardsNasal carriageMRSA isolatesNasal swabsImpact of MRSAMethicillin-resistant Staphylococcus aureus nasal carriageStaphylococcus aureus nasal carriageLow CD4 countRural African hospitalAureus nasal carriageHours of admissionMRSA nasal carriageGovernment district hospitalsStandard disk diffusionImportant nosocomial pathogenRural KwaZulu-NatalAdmission swabCD4 countHospitalised patientsMRSA carriageNosocomial acquisitionTB patientsPrevious hospitalisationMedical charts
2010
Transmission of Drug-Susceptible and Drug-Resistant Tuberculosis and the Critical Importance of Airborne Infection Control in the Era of HIV Infection and Highly Active Antiretroviral Therapy Rollouts
Shenoi SV, Escombe AR, Friedland G. Transmission of Drug-Susceptible and Drug-Resistant Tuberculosis and the Critical Importance of Airborne Infection Control in the Era of HIV Infection and Highly Active Antiretroviral Therapy Rollouts. Clinical Infectious Diseases 2010, 50: s231-s237. PMID: 20397953, PMCID: PMC3029014, DOI: 10.1086/651496.Peer-Reviewed Original ResearchConceptsInfection control strategiesResource-limited settingsHIV infectionInfection controlActive antiretroviral therapy rolloutHuman immunodeficiency virus (HIV) infectionAntiretroviral therapy rolloutTransmission of drugDrug-resistant TBImmunodeficiency virus infectionDrug-resistant tuberculosisHealth care workersAirborne infection controlNosocomial transmissionTuberculosis careVirus infectionCare workersInfectionCurrent outbreakHigh rateTBPotential benefitsMorbidityHIVTuberculosis
2007
Prevention of nosocomial transmission of extensively drug-resistant tuberculosis in rural South African district hospitals: an epidemiological modelling study
Basu S, Andrews JR, Poolman EM, Gandhi NR, Shah NS, Moll A, Moodley P, Galvani AP, Friedland GH. Prevention of nosocomial transmission of extensively drug-resistant tuberculosis in rural South African district hospitals: an epidemiological modelling study. The Lancet 2007, 370: 1500-1507. PMID: 17964351, PMCID: PMC3711808, DOI: 10.1016/s0140-6736(07)61636-5.Peer-Reviewed Original ResearchMeSH KeywordsCross InfectionHospitals, DistrictHumansModels, TheoreticalRural HealthSouth AfricaTuberculosis, Multidrug-ResistantConceptsInfection control strategiesDrug-resistant tuberculosisXDR tuberculosisTuberculosis casesTuberculosis transmissionRural South African district hospitalSouth African district hospitalMask useTugela FerryAfrican district hospitalEffects of HIVInfection control measuresDrug resistance testingCommunity-based dataResource-limited settingsEpidemiological modelling studyCommunity-based programsAntiretroviral therapyNosocomial transmissionHospitalisation timeHIV treatmentOutpatient therapyDistrict hospitalTuberculosis epidemicHospital staff
1984
AIDS Precautions for Other High-Risk Groups?
Klein R, Friedland G. AIDS Precautions for Other High-Risk Groups? Infection Control And Hospital Epidemiology 1984, 5: 466-466. PMID: 6567609, DOI: 10.1017/s0195941700060847.Peer-Reviewed Original ResearchNosocomial Endocarditis
Friedland G, von Reyn C, Levy B, Arbeit R, Dasse P, Crumpacker C. Nosocomial Endocarditis. Infection Control And Hospital Epidemiology 1984, 5: 284-288. PMID: 6564081, DOI: 10.1017/s0195941700060343.Peer-Reviewed Original ResearchConceptsCommunity-acquired endocarditisNosocomial endocarditisIntracardiac prosthetic materialNosocomial infective endocarditisPercent of patientsValvular heart diseaseBeth Israel HospitalSite of originClinical presentationInfective endocarditisUrinary sourceHeart diseaseProsthetic valvesEndocarditisInvasive proceduresGreater incidenceHigh mortalityPatientsProsthetic materialIsrael HospitalBacteremiaSeven-year periodDiseaseTherapeutic practiceHospital
1981
Infective endocarditis: an analysis based on strict case definitions.
Von Reyn C, Levy B, Arbeit R, Friedland G, Crumpacker C. Infective endocarditis: an analysis based on strict case definitions. Annals Of Internal Medicine 1981, 94: 505-18. PMID: 7011141, DOI: 10.7326/0003-4819-94-4-505.Peer-Reviewed Original ResearchConceptsStrict case definitionValvular diseaseCase definitionAdvanced mean ageShorter mean durationNosocomial endocarditisProsthesis endocarditisNeurologic eventsPossible endocarditisCardiac surgeryHeart failureInfective endocarditisMean ageMean durationEarly recognitionClinical studiesEndocarditisHigh incidenceInvasive proceduresViridans streptococciLarge seriesSuspect casesStaphylococcus aureusMortalityDisease