2021
A layered single-side readout depth of interaction time-of-flight-PET detector
Bläckberg L, Sajedi S, Fakhri G, Sabet H. A layered single-side readout depth of interaction time-of-flight-PET detector. Physics In Medicine And Biology 2021, 66: 045025. PMID: 33570050, PMCID: PMC8130834, DOI: 10.1088/1361-6560/abd592.Peer-Reviewed Original ResearchConceptsDepth of interactionMulti-pixel photon counterDepth-of-interaction determinationDepth-of-interaction informationTime resolutionTime resolution valuesReduced crystal thicknessNon-DOI detectorsOptical photonsScintillator arrayPET detectorsPhoton counterCrystal pixelsReadout schemeCrystal arrayCrystal thicknessTransport simulationsDetectorPhotodetector arrayReadoutPixel sizePhotodetectorsResolution valuesFirst layerSignal amplitude
2016
Validation of Bayesian analysis of compartmental kinetic models in medical imaging
Sitek A, Li Q, Fakhri G, Alpert N. Validation of Bayesian analysis of compartmental kinetic models in medical imaging. Physica Medica 2016, 32: 1252-1258. PMID: 27692754, PMCID: PMC5720163, DOI: 10.1016/j.ejmp.2016.09.010.Peer-Reviewed Original ResearchConceptsAccurate estimation of uncertaintyComputer simulationsMedical imagesPosterior distributionDistributed noiseTime series of imagesClosed-formSeries of imagesData setsKinetic parametersMarkov chain Monte Carlo methodsPosterior distributions of kinetic parametersNon-linear least squares methodAccurate estimationComputerLeast-squares methodKinetic modelEstimation of kinetic parametersF18-fluorodeoxyglucoseBayesian estimationImagesStatistical inferenceMonte Carlo methodEstimates of uncertaintyInformation