2023
Detailed radiosynthesis of [18F]mG4P027 as a positron emission tomography radiotracer for mGluR4
Wang J, Moon S, Cleary M, Shoup T, Fakhri G, Zhang Z, Brownell A. Detailed radiosynthesis of [18F]mG4P027 as a positron emission tomography radiotracer for mGluR4. Journal Of Labelled Compounds And Radiopharmaceuticals 2023, 66: 34-40. PMID: 36593743, PMCID: PMC9985952, DOI: 10.1002/jlcr.4011.Peer-Reviewed Original Research
2022
Automation of generative adversarial network-based synthetic data-augmentation for maximizing the diagnostic performance with paranasal imaging
Kong H, Kim J, Moon H, Park H, Kim J, Lim R, Woo J, Fakhri G, Kim D, Kim S. Automation of generative adversarial network-based synthetic data-augmentation for maximizing the diagnostic performance with paranasal imaging. Scientific Reports 2022, 12: 18118. PMID: 36302815, PMCID: PMC9613909, DOI: 10.1038/s41598-022-22222-z.Peer-Reviewed Original ResearchConceptsSynthetic data augmentationData augmentationLack of training dataConventional data augmentationDeep learning methodsTraining dataLearning methodsPipeline approachAlgorithm trainingGraphical dataAutomationWaters' view radiographsModel performanceAutomated pipelinePerformancePerformance parametersAlgorithmDatasetAugmentationDataMethodPipelineRulesIndustrial workers
2017
A report of the automated radiosynthesis of the tau positron emission tomography radiopharmaceutical, [18F]‐THK‐5351
Neelamegam R, Yokell D, Rice P, Furumoto S, Kudo Y, Okamura N, Fakhri G. A report of the automated radiosynthesis of the tau positron emission tomography radiopharmaceutical, [18F]‐THK‐5351. Journal Of Labelled Compounds And Radiopharmaceuticals 2017, 60: 140-146. PMID: 27859483, DOI: 10.1002/jlcr.3482.Peer-Reviewed Original ResearchConceptsO-THPNucleophilic fluorination reactionsHydrochloric acidFluorination reactionDilute hydrochloric acidSemi-preparative high-performance liquid chromatographyTosylate precursorHigh-performance liquid chromatographyUncorrected radiochemical yieldDimethyl sulfoxideRadiochemical yieldRadiosynthesis moduleMulti-center trialLiquid chromatographyAutomated radiosynthesisRadiosynthesisPositron emission tomography radiopharmaceuticalsPET imaging agentUnited States Pharmacopeia