2017
Guest Editorial Low-Dose CT: What Has Been Done, and What Challenges Remain?
Liang J, La Riviere P, Fakhri G, Glick S, Siewerdsen J. Guest Editorial Low-Dose CT: What Has Been Done, and What Challenges Remain? IEEE Transactions On Medical Imaging 2017, 36: 2409-2416. DOI: 10.1109/tmi.2017.2768978.Peer-Reviewed Original ResearchCone-beam CTMulti-detector row CTDiscovery of X-raysIntroduction of computed tomographyMonitoring of therapeutic responseMulti-detector-rowImage-guided interventionsProjection dataMagnetic resonance imagingPositron emission tomographyTherapeutic responseEmergency examinationTreatment planningVolumetric imagesDiagnostic imagingEmission tomographyImaging modalitiesResonance imagingX-rayMedical imaging modalitiesCTTomographyTomographic imagesPositronJoint reconstruction of Ictal/inter‐ictal SPECT data for improved epileptic foci localization
Rakvongthai Y, Fahey F, Borvorntanajanya K, Tepmongkol S, Vutrapongwatana U, Zukotynski K, Fakhri G, Ouyang J. Joint reconstruction of Ictal/inter‐ictal SPECT data for improved epileptic foci localization. Medical Physics 2017, 44: 1437-1444. PMID: 28211105, PMCID: PMC5462456, DOI: 10.1002/mp.12167.Peer-Reviewed Original ResearchConceptsSPECT reconstruction methodDifferential imagingLow-noise datasetConventional subtraction methodLesion contrastSPECT projection dataEpileptic focus localizationHoffman phantomPatient studiesReconstruction methodJoint methodSPECT projectionsHead phantomPhantom locationsSubtraction methodPhantom studyNuclear medicine physiciansAttenuation backgroundPhantomConventional subtraction approachFocus localizationConventional subtractionReceiver operating characteristicLow noiseProjection data
2013
Simultaneous 99mTc‐MDP/123I‐MIBG tumor imaging using SPECT‐CT: Phantom and constructed patient studies
Rakvongthai Y, Fakhri G, Lim R, Bonab A, Ouyang J. Simultaneous 99mTc‐MDP/123I‐MIBG tumor imaging using SPECT‐CT: Phantom and constructed patient studies. Medical Physics 2013, 40: 102506. PMID: 24089927, PMCID: PMC3785531, DOI: 10.1118/1.4820977.Peer-Reviewed Original ResearchConceptsScatter correctionDual-radionuclideContrast recoveryPhantom studyAnthropomorphic torso phantomPatient studiesTumor uptakeTumor imagingSPECT projectionsTorso phantomMonte-CarloPhantom dataPhantomIterative reconstructionOSEMProjection dataDR dataIncrease patient throughputNoise realizationsSPECT-CTImage reconstructionClinical studiesTumorTumor projectionPoisson noise
2007
Fast Monte Carlo based joint iterative reconstruction for simultaneous SPECT imaging
Ouyang J, Fakhri G, Moore S. Fast Monte Carlo based joint iterative reconstruction for simultaneous SPECT imaging. Medical Physics 2007, 34: 3263-3272. PMID: 17879789, DOI: 10.1118/1.2756601.Peer-Reviewed Original ResearchConceptsMC-JOSEMEnergy windowFast Monte CarloSignal-to-noise ratioScatter correction methodOrdered-subsets expectation-maximizationMonte CarloOrdered-subsets expectation-maximization algorithmIterative reconstruction algorithmPrimary photonsReconstruction algorithmPhoton transportSeptal penetrationDetector responseMC simulationsIterative reconstructionAttenuation distributionStandard OSEMPhotonsProjection dataPatient-specific activityDetectorReconstructed imagesScatteringEstimation of scattering