2024
Speech motion anomaly detection via cross-modal translation of 4D motion fields from tagged MRI
Liu X, Xing F, Zhuo J, Stone M, Prince J, El Fakhri G, Woo J. Speech motion anomaly detection via cross-modal translation of 4D motion fields from tagged MRI. Proceedings Of SPIE--the International Society For Optical Engineering 2024, 12926: 129262w-129262w-5. PMID: 39238547, PMCID: PMC11377028, DOI: 10.1117/12.3006874.Peer-Reviewed Original ResearchCross-modal translationHealthy individualsTongue cancer patientsMotion fieldOut-of-distributionOne-class SVMPatient dataAnomaly detectionAnomaly detectorCancer patientsTagged MRISpeech-related disordersGeneralization capabilityReconstruction qualitySpeech qualityArticulatory-acoustic relationsPatientsSpeech waveformTraining setInnovative treatmentsMRITest setMotion patternsArticulatory featuresTraining translators
2022
Cardiac PET/MR Basics
Petibon Y, Ma C, Ouyang J, El Fakhri G. Cardiac PET/MR Basics. 2022, 21-35. DOI: 10.1007/978-3-031-09807-9_2.Peer-Reviewed Original ResearchMeasuring organ motionPET motion correctionFront-end electronicsScintillation detectorOrgan motionMotion correctionAttenuation correctionPET/MR scannersAbility of MRISimultaneous imaging modalityPET/MR technologyAttenuation propertiesHybrid PET/MR scannerPET/MRPre-clinicalImaging modalitiesClinical applicationMRIOrgan systemsCardiac applicationsImaging opportunitiesCorrectionDetectorSpatiotemporal resolutionElectron
2020
Evaluation of the potassium channel tracer [18F]3F4AP in rhesus macaques
Guehl N, Ramos-Torres K, Linnman C, Moon S, Dhaynaut M, Wilks M, Han P, Ma C, Neelamegam R, Zhou Y, Popko B, Correia J, Reich D, Fakhri G, Herscovitch P, Normandin M, Brugarolas P. Evaluation of the potassium channel tracer [18F]3F4AP in rhesus macaques. Cerebrovascular And Brain Metabolism Reviews 2020, 41: 1721-1733. PMID: 33090071, PMCID: PMC8221756, DOI: 10.1177/0271678x20963404.Peer-Reviewed Original ResearchConceptsFocal brain injuryMyelin repair therapyContributions of demyelinationDrivers of disabilityImaging demyelinationBrain injuryMeasurements of molecular changesTool's sensitivity to changesLower myelin contentDemyelinating lesionsNeuronal conductionImpaired conductionDemyelinationBrain penetrationGold standardRhesus macaquesInjured areaMultiple sclerosisMolecular changesMyelin sheathNeurological diseasesHigh metabolic stabilityMRI methodsMRIInjury
2017
Subject-specific anatomical assessment of the human tongue in amyotrophic lateral sclerosis (ALS) by high-resolution MRI and diffusion tensor imaging
Lee E, Xing F, Ahn S, Reese T, Wang R, Green J, Atassi N, Wedeen V, Fakhri G, Woo J. Subject-specific anatomical assessment of the human tongue in amyotrophic lateral sclerosis (ALS) by high-resolution MRI and diffusion tensor imaging. The Journal Of The Acoustical Society Of America 2017, 142: 2639-2639. DOI: 10.1121/1.5014672.Peer-Reviewed Original ResearchHigh-resolution MRIDiffusion tensor imagingAmyotrophic lateral sclerosis subjectsAmyotrophic lateral sclerosisTensor imagingAmyotrophic lateral sclerosis patientsLateral sclerosisAnatomical assessmentSuperior longitudinal muscleNon-invasive imagingDeformable registrationMotor neuronsLongitudinal muscleFractional anisotropyMuscle fibersIrreversible neurological disorderB0 imagesNeurological disordersHuman tongueMRIMotor cortexTongueSclerosisMuscleAnatomical differences