2019
Multi-Modal Signatures of Tau Pathology, Neuronal Fiber Integrity, and Functional Connectivity in Traumatic Brain Injury
Wooten D, Ortiz-Terán L, Zubcevik N, Zhang X, Huang C, Sepulcre J, Atassi N, Johnson K, Zafonte R, Fakhri G. Multi-Modal Signatures of Tau Pathology, Neuronal Fiber Integrity, and Functional Connectivity in Traumatic Brain Injury. Journal Of Neurotrauma 2019, 36: 3233-3243. PMID: 31210098, PMCID: PMC6857466, DOI: 10.1089/neu.2018.6178.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryTraumatic brain injury subjectsDistribution volume ratioWhite matter integrityFunctional connectivityDiffusion tensor imagingPositron emission tomographyTBI subjectsResting-state functional magnetic resonance imagingResting state functional connectivityFunctional magnetic resonance imagingFractional anisotropyDecreased white matter integrityGroup of TBI subjectsIncreased functional connectivityFunctional MRI resultsGraph theory metricsBrain injuryLiving human brainMagnetic resonance imagingNoninvasive neuroimaging techniquesBrain regionsFunctional MRINeuroimaging techniquesDiffusion tractography imaging
2017
Subject-specific anatomical assessment of the human tongue in amyotrophic lateral sclerosis (ALS) by high-resolution MRI and diffusion tensor imaging
Lee E, Xing F, Ahn S, Reese T, Wang R, Green J, Atassi N, Wedeen V, Fakhri G, Woo J. Subject-specific anatomical assessment of the human tongue in amyotrophic lateral sclerosis (ALS) by high-resolution MRI and diffusion tensor imaging. The Journal Of The Acoustical Society Of America 2017, 142: 2639-2639. DOI: 10.1121/1.5014672.Peer-Reviewed Original ResearchHigh-resolution MRIDiffusion tensor imagingAmyotrophic lateral sclerosis subjectsAmyotrophic lateral sclerosisTensor imagingAmyotrophic lateral sclerosis patientsLateral sclerosisAnatomical assessmentSuperior longitudinal muscleNon-invasive imagingDeformable registrationMotor neuronsLongitudinal muscleFractional anisotropyMuscle fibersIrreversible neurological disorderB0 imagesNeurological disordersHuman tongueMRIMotor cortexTongueSclerosisMuscleAnatomical differences