2024
DIANA - Detectability Investgations using Artificial Nodal Additions
Bayerlein R, Xia M, Xie H, Spencer B, Ouyang J, Fakhri G, Nardo L, Liu C, Badawi R. DIANA - Detectability Investgations using Artificial Nodal Additions. 2024, 00: 1-1. DOI: 10.1109/nss/mic/rtsd57108.2024.10657528.Peer-Reviewed Original ResearchContrast recovery coefficientContrast-to-noise ratioLesion-to-background ratioList-mode dataTotal-body PET/CT scannerPositron emission tomographyContrast recoveryOSEM algorithmPatient motionPET/CT scannerArtificial lesionsImage quality metricsLesion detectionQuantitative accuracyPositron emission tomography scanRecovery coefficientCount densityImage contrastBody mass indexImage noisePositron emission tomography imaging techniquesFrame lengthImage smoothingActivity concentrationsAccuracy of lesion detection
2023
Imaging Performance of the Fully Assembled Ultra-High Resolution (UHR) Brain PET scanner
Loignon-Houle F, Toussaint M, Beaudoin J, Gaudreault M, Doyon V, Leroux J, Auger E, Thibaudeau C, Arpin L, Croteau E, Espinosa-Bentancourt E, Samson A, Bouchard J, Espagnet R, Viscogliosi N, Pepin C, Labrecque V, Paulin C, Marin T, Ouyang J, Normandin M, Tétrault M, Michaud J, Fontaine R, Fakhri G, Lecomte R. Imaging Performance of the Fully Assembled Ultra-High Resolution (UHR) Brain PET scanner. 2023, 00: 1-1. DOI: 10.1109/nssmicrtsd49126.2023.10338146.Peer-Reviewed Original ResearchBrain PET scannerUltra-high resolutionPET scannerPeak noise-equivalent count rateUltra Micro Hot Spot PhantomNoise-equivalent count rateAxial field-of-viewHot spot phantomHoffman brain phantomSmall-scale structuresCount rateBrain phantomContrast recoveryReadout schemeField of viewBrain PET imagingPhantomExcellent image qualityImaging performanceSpatial resolutionSmall structuresUltrahigh resolutionImage qualityPET imagingLarger rods
2015
National Electrical Manufacturers Association and Clinical Evaluation of a Novel Brain PET/CT Scanner
Grogg K, Toole T, Ouyang J, Zhu X, Normandin M, Li Q, Johnson K, Alpert N, Fakhri G. National Electrical Manufacturers Association and Clinical Evaluation of a Novel Brain PET/CT Scanner. Journal Of Nuclear Medicine 2015, 57: 646-652. PMID: 26697961, PMCID: PMC4818715, DOI: 10.2967/jnumed.115.159723.Peer-Reviewed Original ResearchConceptsNoise-equivalent count rateCount rateLoose cutsMaximum noise-equivalent counting rateSpatial resolutionDetector ringSilicon photomultipliersBrain phantomContrast recoveryAttenuation correctionPET/CT systemCrystal blockPET/CT scannerImage qualityRadial offsetNational Electrical Manufacturers AssociationActivity distributionUnique mobility capabilitiesAxial extentTransverse resolutionPhantomAxial resolutionActivity concentrationsHuman scansLayer 1 cm
2014
Relative role of motion and PSF compensation in whole‐body oncologic PET‐MR imaging
Petibon Y, Huang C, Ouyang J, Reese T, Li Q, Syrkina A, Chen Y, Fakhri G. Relative role of motion and PSF compensation in whole‐body oncologic PET‐MR imaging. Medical Physics 2014, 41: 042503. PMID: 24694156, PMCID: PMC3971824, DOI: 10.1118/1.4868458.Peer-Reviewed Original ResearchConceptsPoint spread function modelRespiratory motionPoint spread functionPET-MR scannersPencil-beam navigator echoesPET-MRMeasurement of respiratory motionPSF modelRespiratory motion correctionDetector blur effectsModel respiratory motionLung-liver interfacePatient studiesLesion contrastSimultaneous PET-MRSource of image degradationWhole-body PET imagingPET reconstruction algorithmMoving lesionsPhantom experiment resultsPET eventsContrast recoveryNavigator echoesIterative reconstruction processMotion correction
2013
Simultaneous 99mTc‐MDP/123I‐MIBG tumor imaging using SPECT‐CT: Phantom and constructed patient studies
Rakvongthai Y, Fakhri G, Lim R, Bonab A, Ouyang J. Simultaneous 99mTc‐MDP/123I‐MIBG tumor imaging using SPECT‐CT: Phantom and constructed patient studies. Medical Physics 2013, 40: 102506. PMID: 24089927, PMCID: PMC3785531, DOI: 10.1118/1.4820977.Peer-Reviewed Original ResearchConceptsScatter correctionDual-radionuclideContrast recoveryPhantom studyAnthropomorphic torso phantomPatient studiesTumor uptakeTumor imagingSPECT projectionsTorso phantomMonte-CarloPhantom dataPhantomIterative reconstructionOSEMProjection dataDR dataIncrease patient throughputNoise realizationsSPECT-CTImage reconstructionClinical studiesTumorTumor projectionPoisson noiseSpatially varying regularization for motion compensated PET reconstruction
Dutta J, Fakhri G, Lin Y, Huang C, Petibon Y, Reese T, Leahy R, Li Q. Spatially varying regularization for motion compensated PET reconstruction. 2011 IEEE Nuclear Science Symposium Conference Record 2013, 2156-2160. DOI: 10.1109/nssmic.2012.6551493.Peer-Reviewed Original ResearchSimulated lung lesionsRegularization schemeSpatially varying regularizationUngated reconstructionTorso phantomImage reconstruction problemContrast recoverySacrificing signal-to-noise ratioPET reconstructionSignal-to-noise ratioAnalytical approximationReconstruction frameworkQuadratic penaltyDiagonal elementsReconstruction problemLocal impulse responseCardiac motionRegularization approachReconstructed imagesFisher information matrixAutomated fashionPET imagingImpulse responseDegree of smoothnessInformation matrixCardiac motion compensation and resolution modeling in simultaneous PET-MR: a cardiac lesion detection study
Petibon Y, Ouyang J, Zhu X, Huang C, Reese T, Chun S, Li Q, Fakhri G. Cardiac motion compensation and resolution modeling in simultaneous PET-MR: a cardiac lesion detection study. Physics In Medicine And Biology 2013, 58: 2085-2102. PMID: 23470288, PMCID: PMC3657754, DOI: 10.1088/0031-9155/58/7/2085.Peer-Reviewed Original ResearchConceptsContrast recoveryDetector point spread functionPartial volume effectsK-spaceMotion compensationB-spline registrationLesion-detection studiesCardiac motion compensationPET-MR scannersSimultaneous PET-MRPET contrastIterative reconstruction frameworkPoint spread functionMotion correctionPET countsNon-rigid B-spline registrationCardiac phantomPSF modelPET-MRMotion deblurringReconstruction frameworkSystem matrixCardiac PETSpread functionDefect detection